Ihor Yurkevych

Academic rank,

Teaching Assistant

CVPublicationsContacts

Studied at the Department of Biochemistry and Biotechnology of PNU in 2006-2011. There, graduated from postgraduate studies in 2014. 2013-2014 – Scholar of the Cabinet of Ministers of Ukraine. 2014-2018, worked as a Leading specialist of the educational and scientific laboratory of the Department of Biochemistry and Biotechnology of the PNU. 2016-2017 visiting researcher at the Max Planck Institute for Immunobiology and Epigenetics (Freiburg, Germany). Also, from 2017 to 2020, worked as a researcher at the PNU. Executor of domestic and international research projects. At PNU, teaches a number of academic disciplines, in particular: introduction to modern experimental biology, bioinformatics, molecular biology, professional English, genetics, cell biology, virology, basics of clinical biochemistry, microbiology, introduction to biochemistry (in English), laboratory practicum in biochemistry.

Scientific interests: regulation of molecular and epigenetic mechanisms of nutrition, metabolism and aging; age-related diseases; bioinformatic tools for analysis of various types of sequencing.

 

Selected publications

Publications: 16 articles, H-index 10 (Scopus).

https://orcid.org/0000-0003-3071-0014

  1. Strilbytska, O. M., Semaniuk, U., Yurkevych, I., Glovyak, A., Gospodaryov, D., Bayliak, M. M., & Lushchak, O. (2024). 2, 4-Dinitrophenol is toxic on a low caloric diet but extends lifespan of Drosophila melanogaster on nutrient-rich diets without an impact on metabolism. https://doi.org/10.21203/rs.3.rs-4859683/v1
  2. Strilbytska, O., Yurkevych, I., Semaniuk, U., Gospodaryov, D., Simpson, S. J., & Lushchak, O. (2024). Life-History Trade-Offs in Drosophila: Flies Select a Diet to Maximize Reproduction at the Expense of Lifespan. The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, 79(5), glae057. https://doi.org/10.1093/gerona/glae057
  3. Berezovskyi, V. V., Yurkevych, I. S., & Lushchak, O. V. (2024). LEVELS OF CARBOHYDRATES IN SHORT-LIVED STRAIN OF Drosophila melanogaster. Biotechnologia Acta, 17(2), 21-23. https://doi.org/10.15407/biotech17.02.021
  4. Stefanyshyn, N., Strilbytska, O., Burdyliuk, N., Zadorozhna, O., Bubalo, V., Yurkevych, I., & Lushchak, O. (2024). DIETARY PROTEIN-TO-CARBOHYDRATE RATIO AFFECTS DEVELOPMENT AND METABOLISM IN DROSOPHILA LARVAE AND IMAGO. Біологічні студії/Studia Biologica, 18(1), 69-82. http://dx.doi.org/10.30970/sbi.1801.753
  5. Matskevych V, Kamyshnyi O, Vasylyk VM, Grynovska MB, Lenchuk T, Fishchuk R, Gospodaryov D, Yurkevych I, Strilbytska O, Petakh P, Lushchak O (2023) Morphological prediction of lethal outcomes in the evaluation of lung tissue structural changes in patients on respiratory support with СOVID-19: Ukrainian experience. Pathology-Research and Practice, 245, 154471.
  6. Yurkevych IS, Gray LJ, Gospodaryov DV, Burdylyuk NI, Storey KB, Simpson SJ, Lushchak OV (2020) Development of fly tolerance to consuming a high-protein diet requires physiological, metabolic and transcriptional changes. Biogerontology 21 (5), 619-636.
  7. Gospodaryov DV, Strilbytska OM, Semaniuk UV, Perkhulyn NV, Rovenko BM, Yurkevych IS, Barata AG, Dick TP, Lushchak OV, Jacobs HT (2020) Alternative NADH dehydrogenase extends lifespan and increases resistance to xenobiotics in Drosophila. Biogerontology 21(2), 155-171.
  8. Lushchak O, Strilbytska O, Koliada A, Zayachkivska A, Burdyliuk N, Yurkevych I, Storey KB, Vaiserman A (2020) Nanodelivery of phytobioactive compounds for treating aging-associated disorders. Geroscience 42, 117–139.
  9. Strilbytska O, Velianyk V, Burdyliuk N, Yurkevych IS, Vaiserman A, Storey KB, Pospisilik A, Lushchak O (2020) Parental dietary protein-to-carbohydrate ratio affects offspring lifespan and metabolism in drosophila. Comp Biochem Physiol, Part A Mol Integr Physiol 241, 110622.
  10. Strilbytska OM, Semaniuk UV, Storey KB, Yurkevych IS, Lushchak O (2020) Insulin Signaling in Intestinal Stem and Progenitor Cells as an Important Determinant of Physiological and Metabolic Traits in Drosophila. Cells 9.
  11. Gubina N, Naudi A, Stefanatos R, Jove M, Scialo F, Fernandez-Ayala DJ, Rantapero T, Yurkevych IS, Portero-Otin M, Nykter M, Lushchak O, Navas P, Pamplona R, Sanz A (2019) Essential Physiological Differences Characterize Short- and Long-Lived Strains of Drosophila melanogaster. J. Gerontol. A Biol Sci Med Sci 74, 1835–1843.
  12. Lushchak O, Strilbytska OM, Yurkevych IS, Vaiserman AM, Storey KB (2019) Implications of amino acid sensing and dietary protein to the aging process. Exp Gerontol 115, 69–78.
  13. Semaniuk U, Feden’ko K, Yurkevych IS, Storey KB, Simpson SJ & Lushchak OV (2018) Within‐diet variation in rates of macronutrient consumption and reproduction does not accompany changes in lifespan in Drosophila melanogaster. Entomol Exp Appl, 166(1), 74-80.
  14. Semaniuk UV, Gospodaryov DV, Feden’ko KM, Yurkevych IS, Vaiserman AM, Storey KB, Simpson SJ & Lushchak OV (2018) Insulin-like peptides regulate feeding preference and metabolism in Drosophila. Front Physiol, 9.
  15. Lushchak OV, Gospodaryov DV, Yurkevych IS & Storey KB (2016) Oxidized lipids did not reduce lifespan in the fruit fly, Drosophila melanogaster. Arch Insect Biochem Physiol. 91(1), 52-63.
  16. Rovenko BM, Kubrak OI, Gospodaryov DV, Perkhulyn NV, Yurkevych IS, Sanz A, Lushchak OV & Lushchak VI (2015) High sucrose consumption promotes obesity whereas its low consumption induces oxidative stress in Drosophila melanogaster. J Insect Physiol 79, 42-54.
  17. Yurkevych IS (2015) Oxidative stress in muscle growth and adaptation to physical exercise. JPNU 2(1), 61-69.
  18. Rovenko BM, Kubrak OI, Gospodaryov DV, Yurkevych IS, Sanz A, Lushchak OV & Lushchak VI (2015) Restriction of glucose and fructose causes mild oxidative stress independently of mitochondrial activity and reactive oxygen species in Drosophila melanogaster. Comp Biochem Physiol A Mol Integr Physiol 187, 27–39.
  19. Lushchak OV, Gospodaryov DV, Rovenko BM, Yurkevych IS, Perkhulyn NV & Lushchak VI (2014) Specific dietary carbohydrates differentially influence the life span and fecundity of Drosophila melanogaster. J Gerontol A Biol Sci Med Sci 69(1), 3-12.
  20. Gospodaryov DV, Yurkevych IS, Jafari M, Lushchak VI & Lushchak OV (2013) Lifespan extension and delay of age-related functional decline caused by Rhodiola rosea depends on dietary macronutrient balance. Longevity & healthspan 2:5.
  21. Lushchak OV, Gospodaryov DV, Rovenko BM, Glovyak AD, Yurkevych IS, Klyuba VV, Shcherbij MV & Lushchak VI (2012) Balance between macronutrients affects lifespan and functional senescence in fruit fly Drosophila melanogaster. J Gerontol A Biol Sci Med Sci 67, 118–125.

E-mail: ihor.yurkevych@pnu.edu.ua

Tel: +38 0342 59 61 71

Vasyl Stefanyk Precarpathian National University