Prof. Halyna Semchyshyn

HALYNA M. SEMCHYSHYN

Professor, D.Sc. 

 

CVPublicationsContacts

І. ACADEMIC EDUCATION

Field of study – Analytical Chemistry
1985-1990, Chernivtsi State University (Ukraine, USSR)

MSc Thesis: “Peculiarities of Ti2+ and Ni2+adsorbtion on SiO2, TiO2-SiO2 and NiO2-SiO2 nano-oxides”, (in Ukrainian). Advisors: Prof., D.Sci. Yaroslav S. Mazurkevych and Dr. Anatolij H. Voloshchuk, Dept. of Analitycal Chemistry, Faculty of Chemistry, Chernivtsy State University (Ukraine, USSR)

ІІ. SCIENTIFIC DEGREES
Field of study – Biochemistry
2011-2014, D.Sc. Scholarship, Dept. of Biochemistry and Biotechnology, Precarpathian National University (Ukraine)

D.Sc. Thesis: “Molecular mechanisms of the yeast Saccharomyces cerevisiae adaptation to stressful factors” (in Ukrainian). Defence: November 4, 2015, Yuriy Fedkovych Chernivtsi National University (Ukraine). Advisor: Prof., D.Sci. Volodymyr I. Lushchak, Dept. of Biochemistry, Precarpathian National University (Ukraine).

Field of study – Biochemistry
1993-1999 (1995-1998 child care period), PhD Scholarship, Dept. of Biological and Medical Chemistry, Ivano-Frankivsk Medical State Academy (Ukraine)

PhD Thesis: “Biochemical peculiarities of antioxidant systems of Escherichia coli strains with different sensitivity to oxygen” (in Ukrainian). Defence: December 4, 2002, Yuriy Fedkovych Chernivtsi National University (Ukraine). Advisors: Prof., D.Sci. Volodymyr I. Lushchak, Dept. of Biochemistry, Precarpathian National University (Ukraine) and Prof., D.Sci. Anatolij O. Klymenko, Dept. of Biological and Medical Chemistry, Ivano-Frankivsk Medical State Academy (Ukraine).

III. LANGUAGES
Ukrainian, English, Polish, Russian

IV. PROFESSIONAL EXPERIENCE

11-12/2018   Visiting Professor, Dept. of Gastroenterology, Hepatology and Endocrinology

of Hannover Medical School, Germany.

2017-pres     Professor, Dept. of Biochemistry and Biotechnology, Precarpathian

University, Ivano-Frankivsk, Ukraine.

2011-2014    D.Sc. Scholarship, Dept. of Biochemistry and Biotechnology, Precarpathian

National University, Ukraine.

6, 8/2011 Visiting Professor, Dept. of Biology, Lund University, Lund, Sweden.
2, 8/2010 Visiting Professor, Dept. of Biology, Lund University, Lund, Sweden.
3-5/2010 Visiting Professor, Dept. of Immunology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Cracow, Poland.
6/2009 Visiting Professor, Dept. of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Cracow, Poland.
5-6/2008 Visiting Researcher Fellowship, Dept. of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Cracow, Poland.
5-6/2007 Visiting Researcher, Dept. of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Cracow, Poland.
6/2006 Visiting Researcher, Dept. of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Cracow, Poland.
2/2006 Visiting lecturer, XXXIII Winter School of Biotechnology, Jagiellonian University, Krynica, Poland.
2006- pres Associated Professor, Dept. of Biochemistry and Biotechnology, Precarpathian University, Ivano-Frankivsk, Ukraine.
2003-2006 Senior Teacher, Dept. of Biochemistry, Precarpathian University, Ivano-Frankivsk, Ukraine.
2002-2003 Teacher, Dept. of Biochemistry and Biotechnology, Precarpathian University, Ivano-Frankivsk, Ukraine.
1999-2002 Teacher (part time), Dept. of Biology, Precarpathian University, Ivano-Frankivsk, Ukraine.
1999-2002 Teacher (part time), Dept. of Biochemistry, Ivano-Frankivsk Medical State Academy, Ivano-Frankivsk, Ukraine.
1999-2002 Technician, Dept. of Biology, Precarpathian University, Ivano-Frankivsk, Ukraine.
1993-1999 (1995-1998 child care period) PhD. Student, Dept. of Biological and Medical Chemistry, Ivano-Frankivsk Medical State Academy, Ivano-Frankivsk, Ukraine.
1991-1993 Technician, Dept. of Biological and Medical Chemistry, Ivano-Frankivsk Medical State Academy, Ivano-Frankivsk, Ukraine.
1990-1991 Technician, Dept. of Medical Biology and Genetics, Ivano-Frankivsk Medical State Academy, Ivano-Frankivsk, Ukraine.

V. AWARDS AND GRANTS
“Personalized prevention tools in obesity and diabetes” – a joint Romanian-Ukrainian programme of health education – PrePOD”, 2SOFT/4.1/56, project financed by the European Community under the European Neighborhood Instrument, 2020-2022 (activity manager).

19. “Investigation of biochemical and immunological parameters in young and aged mice with precancerous liver disease”, supported by German Academic Exchange Service (DAAD), Hannover Medical School, Germany, 2019-2020 (with Dr. T. Yevsa).

18. Award from the Ministry of Education and Science of Ukraine, Kyiv, May, 2019.

17. “Development of new non-medicinal methods for correction of metabolic syndrome: normalization of physiological and biochemical indices in animals”, supported by Ministry of Education and Science of Ukraine (#0118U003477), 2018-2020 (researcher).

16. “Interplay between biochemical and immunological processes in mice with precancerous and cancerous liver disease”, supported by German Academic Exchange Service (DAAD), Hannover Medical School, Germany, 2018-2019 (with Prof. V. Lushchak and Dr. T. Yevsa).

15. “Biochemical and immunological processes in mice: impact of Western diet and intermitted fasting”, supported by German Academic Exchange Service (DAAD), Hannover Medical School, Germany, 2017-2018 (with Prof. V. Lushchak and Dr. T. Yevsa).

14. Award from District’s state administration for Scientific Achievements, Ivano-Frankivsk, November, 2017.

13. “Study of molecular mechanisms of adaptation of living organisms to adverse factors and development of opportunities to increase the adaptation potential”, supported by Ministry of Education and Science of Ukraine (#0115U002304), 2015-2017 (researcher).

12. D.Sc. Scholarship, Dept. of Biochemistry and Biotechnology, Precarpathian University, Ivano-Frankivsk, Ukraine. December 2011-November 2014.

11. District’s Premium for Scientific Achievements, Ivano-Frankivsk, September, 2012.

10. Study a novel nutrient assimilation factor (NAF) with potential to influence obesity, VISBY Programme, Lund Univesity, Sweden, 2010-2012 (co-leader of the project).

9. Functional analysis of new acute phase proteins, Marie Curie transfer of knowledge MTKD-CT-2006-042586 (ACUP), Dept. of Immunology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Cracow, Poland, (visiting Professor, 15/03/2010 –15/05/2010).

8. Regulation of free radical processes in living organisms, grant of Ministry of Education
and Science of Ukraine, 2009-2011.

7. Adaptative response of the yeast Saccharomyces cerevisiae to free radicals, grant of Fundamental Researches State Fund, Ukraine, 2008-2009.

6. Scholarship from the Queen Jadwiga Fund of the Jagiellonian University, Cracow, Poland, May-June, 2008.

5. Adaptative response of the yeast Saccharomyces cerevisiae to carbonic radical effect, grant of Fundamental Researches State Fund, Ukraine, 2007.

4. Investigations of oxidative stress in animals and microorganisms in order to diminish its harmful action, grant of Ministry of Education and Science of Ukraine, 2006-2008.

3. Yeast Saccharomyces cerevisiae as a model system to study carbonic radical influence on the eukaryotic cells, grant of Fundamental Researches State Fund, Ukraine, October-December, 2006.

2. Regulation by iron ions of free radical processes in living organisms, grant of Ministry of Education
and Science of Ukraine, 2002-2004

1. PhD. Scholarship, Dept. of Biological and Medical Chemistry, Ivano-Frankivsk Medical State Academy, Ivano-Frankivsk, Ukraine. 1993-1999 (1995-1998 child care period).

VI. CURRENT AREAS OF INTEREST
– Reactive species in biology and medicine
– Biochemical aspects of aging and stress resistance (role of non-enzymatic processes)
– Interplay between carbonyl and oxidative stresses (role of dietary carbohydrates)

VII. CURRENT RESEARCH WORK
– Reactive species in biology and medicine

– Interplay between carbonyl and oxidative stresses (role of dietary carbohydrates)

– Non-enzymatic processes in biology (glycation and free radical oxidation)

– Biochemical aspects of aging and stress resistance

– Mechanisms of hormesis and cross-adaptation

VIII. CONFERENCE ORAL PRESENTATIONS, INVITED SEMINARS AND LECTURES

– “Carbonyl/oxidative stress: Relevance to metabolic disorders”, German-Ukrainian Workshop “Perspectives in Biomedicine with a Focus on Cancer Immunotherapy“, supported by the German Academic Exchange Service (Deutscher Akademischer Austauschdienst, DAAD), Precarpathian National University, Ivano-Frankivsk, Ukraine, 30 June – 6 July, 2019.

– “Metabolism of Glycation Products in Relation to Carbonyl/Oxidative Stress and Associated Pathologies”, XII Ukrainian Biochemical Congress, Ternopil, Ukraine, 30 September – 4 October, 2019.

– “Glycoxidation: interplay between oxygen and carbonyl reactive species”, Institute of Experimental Diabetes Research, Centre of Biochemistry, Hannover High Medical School, 27 November 2018.

– “Biomolecules – molecules of life. Truth about carbohydrates”, Summer School for talented young chemists, Vyznytsia of Chernivtsi Region, 10-11 August, 2018.

– “Western diet (truth and myths) and its impact on health”, for listeners of the “University for everyone” Precarpathian National University, Ivano-Frankivsk, Ukraine, 29 May, 2018.

– “Non-enzymatic processes in living systems: generation of reactive intermediates and their interaction with biomolecules”, V Carpathian Biochemical Summer School, “Modern Experimental Biology”, Precarpathian National University, Ivano-Frankivsk, Ukraine, 26 June – 1 July, 2017.

– “Social, economic and scientific problems with dietary carbohydrates: obesity and diabetes”, German-Ukrainian Workshop “Perspectives for young scientists in life sciences: mastering global challenges of the modern society”, supported by the German Academic Exchange Service (Deutscher Akademischer Austauschdienst, DAAD), Precarpathian National University, Ivano-Frankivsk, Ukraine, 25 -31 July, 2016.

– “Free radicals and reactive metabolites: generation and their interaction with cellular constituents”, IV Carpathian Biochemical Summer School, “Modern Experimental Biology”, Precarpathian National University, Ivano-Frankivsk, Ukraine, 22-27 June, 2016.

– Plenary lecture “Biochemistry – the key for health”, Annual Scientific Conference, Precarpathian National University, Ivano-Frankivsk, Ukraine, 21 March, 2016.

– “Free radicals and reactive oxygen species and their interaction with cells” and “Protection mechanisms against reactive oxygen species”, The Third Carpathian Biochemical Summer School, “Stress, Aging, and Free Radicals”, Precarpathian National University, Ivano-Frankivsk, Ukraine, 29 June-4 July, 2015.
– “ Involvement of reducing monosaccharides in non-enzymatic processes in vitro and in vivo”, XI Ukrainian Biochemical Congress, Kyiv, Ukraine, October 6-10, 2014.
– “Free radicals and reactive oxygen species and their interaction with cells”, “Protection mechanisms against reactive oxygen species”, and “Beneficial functions of reactive oxygen species”. The Second Carpathian Biochemical Summer School, “Investigation of Free Radical Processes in Living Organisms”, Precarpathian National University, Ivano-Frankivsk, Ukraine, 31 June-7 July, 2014.
– “Relationship between oxidative and carbonyl stresses”, International Conference “Environmentally Induced Oxidative Stress in Nature and Experiment”, Delmenhorst, Germany, July 9-10, 2012.
– “Yeast as a model to study age-related metabolic disorders”, International Conference on Advances in Microbiology and Biotechnology for Human and Animal Health, Malmo & Lund, Sweden, 21-22 June 2011.
– “Involvement of carbohydrates in free radical processes”, X Ukrainian Biochemical Congress, Odesa, Ukraine, September 13-17, 2010.
– “Yeast as a model to study human disorders”, Lund University, Sweden, August 20, 2010.
– “Free radicals, antioxidants and immune system” (special lecture course for MS. and Ph.D. students), Jagiellonian University, Cracow, Poland, 03-05/2010.
– “Evaluation of NO and ROS concentration in human and murine materials”, Jagiellonian University, Cracow, Poland, April 21, 2010.
– “Saccharomyces cerevisiae as a model to study molecular mechanisms of cross-adaptation and response to environmental stresses”, 3rd International Ukrainian-Polish Weigl Conference, Odessa, Ukraine, 2009.
– “Relation between carbohydrate metabolism and free radical processes in baker’s yeast”, ХІІ Congress of Ukrainian Microbiology Society, Uzhorod, Ukraine, 2009.
– “Glucose and fructose differently affect baker’s yeast aging”, Jagiellonian University, Cracow, Poland, June 3, 2008.
– “Escherichia coli and Saccharomyces cerevisiae response to oxidative stress”, Jagiellonian University, Cracow, Poland, May 17, 2007.
– “Coordination of superoxide dismutases and catalases in bacteria Escherichia coli and yeast Saccharomyces cerevisiae”, IX Ukrainian Biochemical Congress, Kharkiv, Ukraine, October 24-27, 2006.
– “SoxRS regulon in E. coli response to H2O2-induced stress”, V International Conference “Factors of experimental evolution of organisms”, September 10-16, 2006.

IX. JOURNAL REFEREE

BMC Biochemistry
Central European Journal of Biology
Ukrainian Biochemical Journal
Advances in Research
Nutrition Research
Journal of Pharmacy and Pharmacology
International Journal of Biochemistry Research & Review

X. TEACHING EXPERIENCE

General theoretical and practical courses:

12. “Analytical chemistry”, lectures for biochemists, Dept. of Biochemistry and Biotechnology, Precarpathian University, 2017- pres, Ivano-Frankivsk, Ukraine.
11. “Non-enzymatic processes in biology”, lectures, Dept. of Biochemistry and Biotechnology, Precarpathian University, 2006- pres, Ivano-Frankivsk, Ukraine.
10. “Free radicals, antioxidants and immune system” (special lecture course for Ms. and Ph.D. students), Jagiellonian University, Cracow, Poland, 03-05/2010.
9. “Phys-Chemical methods in biology” – lectures, Dept. of Biochemistry and Biotechnology, Precarpathian University, 2006- pres, Ivano-Frankivsk, Ukraine.
8. “Biochemistry”, general course – lectures & practice, Dept. of Biochemistry and Biotechnology, Precarpathian University, 2006- pres, Ivano-Frankivsk, Ukraine.
7. “Free radical process in biology”, general course – lectures & seminars, Dept. of Biochemistry and Biotechnology, Precarpathian University, 2005- pres, Ivano-Frankivsk, Ukraine.
6. “Bioorganic Chemistry” general course – lectures & practice, Dept. of Biochemistry and Biotechnology, Precarpathian University, 2004-, Ivano-Frankivsk, Ukraine.
5. “Microbiology”, general course – lectures & practice, Dept. of Biochemistry and Biotechnology, Precarpathian University, 2002- pres, Ivano-Frankivsk, Ukraine.
4. “English for Biochemists”, seminars, Dept. of Biochemistry and Biotechnology, Precarpathian University, 2002-pres, Ivano-Frankivsk, Ukraine.
3. “Biochemistry of plants”, general course – lectures & seminars, Dept. of Biochemistry, Precarpathian University, 2002-2004, Ivano-Frankivsk, Ukraine.
2. “Biochemistry of Adaptations”, seminars, Dept. of Soil Science, Precarpathian University, 2002-2004, Ivano-Frankivsk, Ukraine.
1. “Medical biochemistry”, practice, Ivano-Frankivsk Medical State Academy, September 1999 – 2002, Ivano-Frankivsk, Ukraine.

Ph.D. students
2013-2016 Ruslana Vasylkovska – Dept. of Biochemistry and Biotechnology, Precarpathian National University, Ivano-Frankivsk, Ukraine (2016-pres child care period).
2011-2014 Bohdana Valishkevych (Homza) – Dept. of Biochemistry and Biotechnology, Precarpathian National University, Ivano-Frankivsk, Ukraine (Defence: July 27, 2019).
2008−2011 Liudmyla Lozinska (Morhulets) – Dept. of Biochemistry and Biotechnology, Precarpathian National University, Ivano-Frankivsk, Ukraine (Defence: February 11, 2013).

XI. PROFESSIONAL SOCIETIES
Ukrainian Biochemical Society
Society of Microbiologists of Ukraine

XII. PUBLICATIONS
MONOGRAPH CHAPTERS – 5
REVIEWS – 8
EXPERIMENTAL ARTICLES – 41
ABSTRACTS – 36

REVIEWS & MONOGRAPH CHAPTERS

4. Semchyshyn H.M., Lushchak V.I. Interplay between oxidative and carbonyl stresses: molecular mechanisms, biological effects and therapeutic strategies of protection, in book: Oxidative Stress – Molecular Mechanisms and Biological Effects, editors: Lushchak V.I. & Semchyshyn H.M., InTech, 2012, 15-46.

3. Lushchak V.I., Semchyshyn H.M. Introductory chapter, in book: Oxidative Stress – Molecular Mechanisms and Biological Effects, editors: Lushchak V.I. & Semchyshyn H.M., InTech, 2012, 3-12.

2. Lushchak V.I., Semchyshyn H.M., Lushchak O.V. “Classic” methods for measuring of oxidative damage: TBARS, xylenol orange, and protein carbonyls, in textbook: Oxidative Stress in Aquatic Ecosystems, editors: D. Abele, T. Zenteno-Savin, J. Vazquez-Medina, Blackwell Publishing Ltd., 2012, 420-431.

1. Semchyshyn H.M., Bayliak M.M, Lushchak V.I. Starvation in yeasts: biochemical aspects, in book: Biology of Starvation in Humans and Other Organisms, editor: T. C. Merkin, 2011, 103-150.

REVIEWS
6. Semchyshyn H.M. Reactive carbonyl species in vivo: generation and dual biological effects, ScientificWorldJournal – 2014; 2014:417842 (11 pages). IF 1.73

5. Semchyshyn H. Fructation in vivo: detrimental and protective effects of fructose, Biomed Res Int., 2013, 2013:343914 (9 pages). IF 2.706

4. Lozinska L., Semchyshyn H. Biological aspects of non-enzymatic glycosylation, Ukrainian Biochem. J. (Ukrainian), 2012, 84(5), 16-37.

3. Semchyshyn H. Hydrogen peroxide-induced response in E. coli and S. cerevisiae: different stages of the flow of the genetic information, Cent. Eur. J. Biol., 2009, 4(2), 142–153. IF 0.915

2. Abrat O., Semchyshyn H., Lushchak V. Acid stress in the yeast Sacccharomyces cerevisiae, Ukrainian Biochem. J. (Ukrainian), 2008, 80(6), 19-31.

1. Semchyshyn H.M., Lushchak V.I. Oxidative stress and control of catalase activity in Еscherichia coli, Ukrainian Biochem. J. (Ukrainian), 2004, 76(2), 31-42.

EXPERIMENTAL ARTICLES
38. Semchyshyn H.M., Valishkevych B.V. Hormetic effect of H2O2 in S. cerevisiae: involvement of TOR and glutathione reductase, Dose Response, 2016, in press. IF 1.217

37. Valishkevych B.V., Vasylkovska R.A., Lozinska L.M., Semchyshyn H.M. Fructose-induced carbonyl/oxidative stress in S. cerevisiae: involvement of TOR, Biochem. Res. Int., 2016; 2016: 120583 (9 pages).

36. Vasylkovska R., Petriv N., Semchyshyn H. Carbon sources for yeast growth as a precondition of hydrogen peroxide induced hormetic phenotype, Int. J. Microbiol., 2015; 2015: 697813 (8 pages).

35. Vasylkovska R., Burdyliuk N., Semchyshyn H. Involvement of catalase in Saccharomyces cerevisiae hormetic response to hydrogen peroxide, Journal of Vasyl Stefanyk Precarpathian National University, 2015, 2(1), 107-114.

34. Homza B., Vasylkovska R., Semchyshyn H. Defects in TOR regulatory complexes retard
aging and carbonyl/oxidative stress development in yeast Sассharomyces cerevisiae, Ukrainian Biochem. J. (Ukrainian), 2014, 86(1), 85-92.

33. Semchyshyn H., Miedzobrodzki J., Bayliak M., Lozinska L., Homza B. Fructose compared with glucose is more a potent glycoxidation agent in vitro, but not under carbohydrate-induced stress in vivo: potential role of antioxidant and antiglycation enzymes, Carbohydr. Res., 2014, 384, 61-69. IF 2.332

32. Semchyshyn H. Hormetic concentrations of hydrogen peroxide but not ethanol induce cross-adaptation to different stresses in budding yeast, Int. J. Microbiol. – 2014; 2014: 485792 (5 pages).

31. Semchyshyn H. Defects in antioxidant defence enhance glyoxal toxicity in the yeast Saccharomyces cerevisiae, Ukrainian Biochem. J. (Ukrainian), 2013, 85(5), 50-60.

30. Semchyshyn H., Lozinska L. Fructose protects baker’s yeast against peroxide stress: potential role of catalase and superoxide dismutase, FEMS Yeast Res., 2012, 12(7), 761-773. IF 2.818

29. Lozinska L., Semchyshyn H. Fructose as a factor of carbonyl/oxidative stress development and accelerated aging in the yeast Saccharomyces cerevisiae, Ukrainian Biochem. J. (Ukrainian), 2011, 83(4), 67-76.

28. Semchyshyn H., Lozinska L., Miedzobrodzki J., Lushchak V. Fructose and glucose differentially affect aging, carbonyl and oxidative stress parameters in Saccharomyces cerevisiae cells, Carbohydr. Res., 2011, 346(7), 933-938. IF 2.332

27. Semchyshyn H., Abrat O., Inoue Y., Miedzobrodzki J., Lushchak V. Acetate but not propionate induces oxidative stress in bakers’ yeast Saccharomyces cerevisiae, Redox Report, 2011, 16(1), 15-23. IF 1.732

26. Lushchak V., Abrat O., Miedzobrodzki J., Semchyshyn H. Pdr12p-dependent and -independent fluorescein extrusion from baker’s yeast cells, Acta Biochim. Pol. 2008, 55(3), 595-601. IF 1.448

25. Abrat O., Semchyshyn H., Miedzobrodzki J., Lushchak V. Fluorescein transport and antioxidant systems in the yeast Saccharomyces cerevisiae under acid stress, Ukrainian Biochem. J. (Ukrainian), 2008, 80(3), 70-77

24. Bayliak M., Gospodaryov D., Semchyshyn H., Lushchak V. Inhibition of catalase by aminotriazole in vivo results in reduction of glucose-6-phosphate dehydrogenase activity in Saccharomyces cerevisiae cells. Biochemistry (Moscow), 2008, 73(4), 420-426. IF 1.308

23. Lushchak O., Semchyshyn H., Lushchak V. Growth on ethanol results in coordinated S. cerevisiae response to inactivation of gene encoding superoxide dismutases, Redox Report, 2007, 4, 181-188. IF 1.6

22. Bayliak M., Semchyshyn H., Lushchak V. Possible accumulation of non-active molecules of catalase and superoxide dismutase in S. cerevisiae cells under hydrogen peroxide induced stress, Central European Journal of Biology, 2007, 2(3), 326-336. IF 0.25

21. Abrat O., Semchyshyn H., Lushchak V. Acid stress increases the activity of superoxide dismutase and catalase in the yeast Saccharomyces cerevisiae, Ukrainian Biochem. J. (Ukrainian), 2007, 79(2), 18-24.

20. Mandryk S., Lushchak O., Semchyshyn H., Lushchak V. The role of Cu,Zn – and Mn-containg SODs in the yeast Saccharomyces cerevisiae growing on ethanol or glycerol, Microbiol. J. (Ukrainian), 2007, 69(1), 35-42.

19. Bayliak M., Semchyshyn H., Lushchak V. Effect of hydrogen peroxide on antioxidant enzyme activities in Saccharomyces cerevisiae is strain-specific, Biochemistry (Moscow), 2006, 71(9), 1243-1252. IF 1.368

18. Semchyshyn H. oxyR and soxRS regulons are responsible for Escherichia coli protection against H2O2–induced stress // Factors of experimental evolution, -Kyiv: Logos, 2006, 3, 429-432.

17. Bayliak M., Semchyshyn H., Lushchak V. Role of catalase and superoxide dismutase in the yeast Saccharomyces cerevisiae response to hydrogen peroxide in exponential phase, Ukrainian Biochem. J., 2006 (Ukrainian), 78(2), 66-72.

16. Lushchak V., Semchyshyn H., Mandryk S., Lushchak O. Diethyldithiocarbamate inhibits in vivo Cu,Zn-superoxide dismutase and perturbs free radical processes in the yeast Saccharomyces cerevisiae cells, Biochem. Biophys. Res. Commun. 2005, 338, 1739-1744. IF 2.749

15. Semchyshyn H.М., Bagnyukova T.V., Storey K., Lushchak V.І. Hydrogen peroxide increases the activities of soxRS regulon enzymes and the levels of oxidized proteins and lipids in Escherichia coli, Cell. Biol. Intern, 2005, 29, 898-902 IF 1.933

14. Semchyshyn H.M., Bagnyukova T.V., LushchakV.I. Involvement of soxRS regulon in response of Escherichia coli to oxidative stress induced by hydrogen peroxide, Biochemistry (Moscow), 2005, 70(11), 1238-1244. IF 0.858

13. Bayliak M., Abrat O., Semchyshyn H., Lushchak V. Survival and antioxidant defense of the yeast Saccharomyces cerevisiae under starvation and oxidative stress, Ukrainian Biochem. J., 2005 (Ukrainian), 77(4), 97-102.
12. Lushchak V., Semchyshyn H., Mandryk S., Lushchak O. Possible role of superoxide dismutases in the yeast Saccharomyces cerevisiae under respiratory conditions, Arch. Biochem. Biophys., 2005, 441, 35-40. IF 2.386

11. Semchyshyn H.M., LushchakV.I., Storey K. Possible reasons for difference in sensitivity to oxygen of two Escherichia coli strains, Biochemistry (Moscow), 2005, 70(4), 424-431. IF 0.858

10. Abrat O.B., Semchyshyn H.M., Lushchak V.I. Survival and antioxidant defense of Escherichia coli in response to alloxan exposure, Ukrainian Biochem. J. (Ukrainian), 2005, 77(2), 122-128.

9. Semchyshyn H.M., Lushchak V.I. Effect of protonofore 2,4-dinitrophenol on catalase activity of intact Еscherichia coli bacteria, Ukrainian Biochem. J. (Ukrainian), 2004, 76(3), 42-48.

8. Semchyshyn H.M., Bagnyukova T.V. Oxidative stress effect on catalase activity with two pH-optimums in Escherichia coli, Proceedings of Precarpathian University: Biology (Ukrainian), 2003, 3, 124-130.

7. Semchyshyn H.M., Dyljovyj M.V., Lushchak V.I. pH-dependency of Еscherichia coli catalase activity under cultivation conditions modification, Ukrainian Biochem. J. (Ukrainian), 2002, 74(5), 34-41.

6. Semchyshyn H.M., Dyljovyj M.V., Lushchak V.I. Distribution of the activity of two catalase forms in Еscherichia соlі cells, Experimental and Clinical Physiology and Biochemistry (Ukrainian), 2002, 1, 20-23.

5. Semchyshyn H.M., Lushchak V.I. Characteristics of two peaks of catalase activity in Escherichia coli, Medical Chemistry (Ukrainian), 2002, 4(3), 34-37.

4. Semchyshyn H.M. Effect of different oxygen levels on Escherichia coli growth, Proceedings of Precarpathian University: Biology (Ukrainian), 2001, 1, 112-117.

3. Semchyshyn H.M., Dyljovyj M.V., Klymenko A.O., Lushchak V.I. Effect of Еscherichia соlі cell desintegration on some biochemical properties of catalase, Ukrainian Biochem. J. (Ukrainian), 2001, 73(1), 24-28.

2. Semchyshyn H.M. Antioxidant enzymes of Escherichia coli strains with different sensitivity to oxygen, Bulletin of agricultural microbiology (Ukrainian), 2000, 7, 74-75.

1. Semchyshyn H.M., Klymenko A.O., Lushchak V.I. Effect of oxidative stress on pH-sensitivity of Escherichia coli catalase, Medical Chemistry (Ukrainian), 2000, 2(2), 59-61.