Review and Experimental Articles

  1. Strilbytska O. M.  Stefanyshyn N. P., Semaniuk U. V., Lushchak O. V. Yeast concentration in the diet defines Drosophila metabolism of both parental and offspring generations. Ukr.Biochem. J. 2021; Volume 93, Issue 6, Nov-Dec, pp. 119-129. doi: https://doi.org/10.15407/ubj93.06.119
  2. Strilbytska1 O., Zayachkivska A., Strutynska, T., Semaniuk U., Vaiserman A., Lushchak O. Dietary protein defines stress resistance, oxidative damages and antioxidant defense system in Drosophila melanogaster. Ukr.Biochem.J. 2021; Volume 93, Issue 5, Sep-Oct, pp. 90-101. doi: https://doi.org/10.15407/ubj93.05.090
  3. Mykhailovych V, Kanak A, Cojocaru Ş, Chitoiu-Arsene E-D, Palamaru MN, Iordan A-R, Korovyanko O, Diaconu A, Ciobanu VG, Caruntu G, Lushchak O, Fochuk P, Khalavka Y, Rotaru A. Structural, Optical, and Catalytic Properties of MgCr2O4 Spinel-Type Nanostructures Synthesized by Sol–Gel Auto-Combustion Method. Catalysts. 2021; 11(12):1476. https://doi.org/10.3390/catal11121476
  4. Galkin M, Priss A, Topcheva O, Yushchenko DA, Shvadchak VV. FRET-based assay for intracellular evaluation of α-synuclein aggregation inhibitors. J Neurochem. 2021;159(5):901-912.https://doi.org/10.1111/jnc.15528
  5. Lushchak VI, Duszenko M, Gospodaryov DV, Garaschuk O. Oxidative Stress and Energy Metabolism in the Brain: Midlife as a Turning Point. Antioxidants. 2021; 10(11):1715. https://doi.org/10.3390/antiox10111715
  6. Vaiserman A,  Lushchak O. DNA methylation changes induced by prenatal toxic metal exposure: An overview of epidemiological evidence. Environmental Epigenetics, Volume 7, Issue 1, 2021, dvab007, https://doi.org/10.1093/eep/dvab007
  7. Lushchak VI, Lushchak O. Interplay between reactive oxygen and nitrogen species in living organisms. Chem Biol Interact. 2021 Oct 1;349:109680. doi: 10.1016/j.cbi.2021.109680.
  8. Kamyshnyi O, Matskevych V, Lenchuk T, Strilbytska O, Storey K, Lushchak O. Metformin to decrease COVID-19 severity and mortality: Molecular mechanisms and therapeutic potential. Biomed Pharmacother. 2021 Oct 6;144:112230. doi: 10.1016/j.biopha.2021.112230.
  9. Peteliuk V., Rybchuk L., Bayliak M., Storey K. B. & Lushchak, O. (2021). Natural sweetener Stevia rebaudiana: Functionalities, health benefits and potential risks. EXCLI Journal20, 1412-1430. https://doi.org/10.17179/excli2021-4211
  10. Bayliak, M. M., Dmytriv, T. R., Melnychuk, A. V., Strilets, N. V., Storey , K. B., & Lushchak, V. I. (2021). Chamomile as a potential remedy for obesity and metabolic syndrome. EXCLI Journal20, 1261-1286. https://doi.org/10.17179/excli2021-4013
  11. Strilbytska OM, Strutynska TR,  Semaniuk UV, Burdyliuk NI,  Storey KB,  Lushchak OV (2021). Parental dietary sucrose affects metabolic and antioxidant enzyme activities in DrosophilaEntomological Science  https://doi.org/10.1111/ens.12479
  12. Lushchak, V. I.,  Storey, K. B. (2021). Oxidative stress concept updated: Definitions, classifications, and regulatory pathways implicated . EXCLI Journal20, 956-967. https://doi.org/10.17179/excli2021-3596
  13. Semaniuk U, Strilbytska O, Malinovska K, Storey KB, Vaiserman A, Lushchak V, Lushchak O. (2021) Factors that regulate expression patterns of insulin-like peptides and their association with physiological and metabolic traits in Drosophila. Insect Biochem Mol Biol. 135:103609. https://doi.org/10.1016/j.ibmb.2021.103609
  14. Koliada, A., Moseiko, V., Romanenko, M., Lushchak, O., Kryzhanovska, N., Guryanov, V., Vaiserman, A. (2021). Sex differences in the phylum‐level human gut microbiota composition. BMC microbiology21(1), 1-9.https://doi.org/10.1186/s12866-021-02198-y
  15. Vaiserman, A., Koliada, A., Lushchak, O. (2021). Phyto-nanotechnology in anti-aging medicine. Aging (Albany NY)13(8), 10818. https://doi.org/10.18632/aging.203026
  16. Semaniuk, U., Gospodaryov, D., Mishchanyn, K., Storey, K., & Lushchak, O. (2021). Drosophila insulin-like peptides regulate concentration-dependent changes of appetite to different carbohydrates. Zoology (Jena, Germany)146, 125927. Advance online publication. https://doi.org/10.1016/j.zool.2021.125927
  17. Vaiserman, A., Koliada, A., Lushchak, O., Castillo, M. J. (2021). Repurposing drugs to fight aging: The difficult path from bench to bedside. Medicinal research reviews41(3), 1676–1700. https://doi.org/10.1002/med.21773
  18. Semaniuk, U., Gospodaryov, D., Mishchanyn, K., Storey, K., & Lushchak, O. (2021). Drosophila insulin-like peptides regulate concentration-dependent changes of appetite to different carbohydrates. Zoology (Jena, Germany)146, 125927. Advance online publication. https://doi.org/10.1016/j.zool.2021.125927
  19. Heier, C., Klishch, S., Stilbytska, O., Semaiuk, U., & Lushchak, O. (2021). The Drosophila model to interrogate triacylglycerol biology. Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids, 158924. https://doi.org/10.1016/j.bbalip.2021.158924
  20. Bayliak, M. M., Mosiichuk, N. M., Sorochynska, O. M., Kuzniak, O. V., Sishchuk, L. O., Hrushchenko, A. O., Semchuk, A. O., Pryimak, T. V., Vasylyk, Y. V., Gospodaryov, D. V., Storey, K. B., Garaschuk, O., & Lushchak, V. I. (2021).  Middle aged turn point in parameters of oxidative stress and glucose catabolism in mouse cerebellum during lifespan: minor effects of every-other-day fasting. Biogerontology. 22, 315–328. https://doi.org/10.1007/s10522-021-09918-x
  21. Sorochynska, O. M., Kuzniak, O. V., Bayliak, M. M., Vasylyk, Y. V., Storey, K. B., Lushchak, V. I. (2021). Every-other-day fasting reduces glycolytic capability in the skeletal muscle of young mice. Biologia, 76, 1627–1634. https://doi.org/10.1007/s00424-021-02529-y
  22. Lushchak, V.I. (2021) Interplay between bioenergetics and oxidative stress at normal brain aging. Aging as a result of increasing disbalance in the system oxidative stress–energy provision. Pflugers Arch – Eur J Physiol. 473, 713–722. https://doi.org/10.1007/s00424-021-02531-4
  23. Semchyshyn, H. (2021) Is carbonyl/AGE/RAGE stress a hallmark of the brain aging?. Pflugers Arch – Eur J Physiol. 473, 723–734. https://doi.org/10.1007/s00424-021-02529-y
  24. Semaniuk, U., Piskovatska, V., Strilbytska, O., Strutynska, T., Burdyliuk, N., Vaiserman, A., Bubalo V., Storey K.B. & Lushchak, O. (2021). Drosophila insulin‐like peptides: from expression to functions–a review. Entomologia Experimentalis et Applicata. 169 (2). 195-208. https://doi.org/10.1111/eea.12981
  25. Bayliak MM, Sorochynska OM, Kuzniak OV, Gospodaryov DV, Demianchuk OI, Vasylyk YV, Mosiichuk NM, Storey KB, Garaschuk O, Lushchak VI. (2021). Middle age as a turning point in mouse cerebral cortex energy and redox metabolism: Modulation by every-other-day fasting. Experimental Gerontology, Vol. 145, 111182. https://doi.org/10.1016/j.exger.2020.111182
  26. Bayliak, M. M., Lushchak, V. I. (2021). Pleiotropic effects of alpha-ketoglutarate as a potential anti-ageing agent. Ageing Research Reviews, 101237. https://doi.org/10.1016/j.arr.2020.101237
  27. Nataliia Petriv, Lavinia Neubert, Myroslava Vatashchuk, Kai Timrott, Huizhen Suo, Inga Hochnadel, René Huber, Christina Petzold, Anastasiia Hrushchenko, Andriy S. Yatsenko, Halyna R. Shcherbata, Heiner Wedemeyer, Ralf Lichtinghagen, Halina Falfushynska, Volodymyr Lushchak, Michael P. Manns, Heike Bantel, Halyna Semchyshyn & Tetyana Yevsa (2021) Increase of α-dicarbonyls in liver and receptor for advanced glycation end products on immune cells are linked to nonalcoholic fatty liver disease and liver cancer, OncoImmunology, 10:1, DOI: 10.1080/2162402X.2021.1874159

Monographs and monograph chapters

Lushchak, O., Piskovatska, V., Strilbytska, O., Kindrat, I., Stefanyshyn, N., Koliada, A., … & Vaiserman, A. (2021).  Aspirin as a Potential Geroprotector: Experimental Data and Clinical Evidence. In: Guest P.C. (eds) Reviews on New Drug Targets in Age-Related Disorders. Advances in Experimental Medicine and Biology, vol 1286. Springer, Cham, 145-161. https://doi.org/10.1007/978-3-030-55035-6_11
 Vaiserman A,  Lushchak O, Koliada A,
Chapter 2 – Environmental epigenetic epidemiology,
Editor(s): Trygve O. Tollefsbol, In Translational Epigenetics,
Medical Epigenetics (Second Edition), Academic Press, Volume 29, 2021,
Pages 11-31,
ISBN 9780128239285,