Our publications



Publications indexed in SCOPUS

  1. Demianchuk, O., Vatashchuk, M., Gospodaryov, D., Hurza, V., Ivanochko, M., Derkachov, V., Berezovskyi, V., Lushchak, O., Storey, K. B., Bayliak, M., & Lushchak, V. I. (2024). High-fat high-fructose diet and alpha-ketoglutarate affect mouse behavior that is accompanied by changes in oxidative stress response and energy metabolism in the cerebral cortex. Biochimica et biophysica acta. General subjects1868(1), 130521. https://doi.org/10.1016/j.bbagen.2023.130521
  2. Vatashchuk, M. V., Hurza, V. V., Stefanyshyn, N., Bayliak, M. M., Gospodaryov, D. V., Garaschuk, O., & Lushchak, V. I. (2024). Impact of caloric restriction on oxidative stress and key glycolytic enzymes in the cerebral cortex, liver and kidney of old and middle-aged mice. Neuropharmacology247, 109859. https://doi.org/10.1016/j.neuropharm.2024.109859
  3. Lushchak, O., Velykodna, M., Bolman, S., Strilbytska, O., Berezovskyi, V., & Storey, K. B. (2023). Prevalence of stress, anxiety, and symptoms of post-traumatic stress disorder among Ukrainians after the first year of Russian invasion: a nationwide cross-sectional study. The Lancet regional health. Europe36, 100773. https://doi.org/10.1016/j.lanepe.2023.100773
  4. Galkin, M., Priss, A., Kyriukha, Y., & Shvadchak, V. (2024). Navigating α-Synuclein Aggregation Inhibition: Methods, Mechanisms, and Molecular Targets. Chemical record (New York, N.Y.)24(2), e202300282. https://doi.org/10.1002/tcr.202300282
  5. Strilbytska, O., Semaniuk, U., Gospodaryov, D., Simpson, S. J., & Lushchak, O. (2024). Life history trade-offs in Drosophila: flies select a diet to maximize reproduction at the expense of lifespan. The journals of gerontology. Series A, Biological sciences and medical sciences, Volume 79, Issue 5, May 2024, glae057.  https://doi.org/10.1093/gerona/glae057
  6. Dmytriv, T. R., & Lushchak, V. I. (2024). Potential Biosafety of Mxenes: Stability, Biodegradability, Toxicity and Biocompatibility. Chemical record (New York, N.Y.), e202300338. Advance online publication. https://doi.org/10.1002/tcr.202300338
  7. Strilbytska O, Klishch S, Storey KB, Koliada A, Lushchak O. Intermittent fasting and longevity: From animal models to implication for humans. Ageing Res Rev. 2024;96:102274. https://doi.org/10.1016/j.arr.2024.102274
  8. Danyliuk, N., Lapchuk, I., & Husak, V. (2024). Toxicity of water treated with Fenton-like ferrite catalyst. Physics and Chemistry of Solid State25(1), 170–177. https://doi.org/10.15330/pcss.25.1.170-177
  9. Stefanyshyn, N., Strilbytska, O., Burdyliuk, N., Zadorozhna, O., Bubalo, V., Yurkevych, I., & Lushchak, O. (2024). DIETARY PROTEIN-TO-CARBOHYDRATE RATIO AFFECTS DEVELOPMENT AND METABOLISM IN DROSOPHILA LARVAE AND IMAGO. Біологічні студії/Studia Biologica18(1), 69-82.
    DOI: http://dx.doi.org/10.30970/sbi.1801.753



Publications indexed in SCOPUS

  1. Lushchak, O., Strilbytska, O., & Storey, K. B. (2023). Gender-specific effects of pro-longevity interventions in DrosophilaMechanisms of ageing and development, 209, 111754. https://doi.org/10.1016/j.mad.2022.111754
  2. Bayliak, M. M., Gospodaryov, D. V., & Lushchak, V. I. (2023). Homeostasis of carbohydrates and reactive oxygen species is critically changed in the brain of middle-aged mice: molecular mechanisms and functional reasons. BBA Advances, 100077.https://doi.org/10.1016/j.bbadva.2023.100077
  3. Lushchak, O., Strilbytska, O., Koliada, A., & Storey, K. B. (2023). An orchestrating role of mitochondria in the origin and development of post-traumatic stress disorder. Frontiers in physiology13, 1094076. https://doi.org/10.3389/fphys.2022.1094076
  4. Matskevych, V., Kamyshnyi, O., Vasylyk, V. M., Grynovska, M. B., Lenchuk, T., Fishchuk, R., Gospodaryov, D., Yurkevych, I., Strilbytska, O., Petakh, P., & Lushchak, O. (2023). Morphological prediction of lethal outcomes in the evaluation of lung tissue structural changes in patients on respiratory support with СOVID-19: Ukrainian experience. Pathology, research and practice245, 154471. https://doi.org/10.1016/j.prp.2023.154471
  5. Khatib, I., Horyn, O., Bodnar, O., Lushchak, O., Rychter, P., & Falfushynska, H. (2023). Molecular and biochemical evidence of the toxic effects of terbuthylazine and malathion in zebrafish. Animals : an open access journal from MDPI13(6), 1029. https://doi.org/10.3390/ani13061029
  6. Lushchak, O., Schosserer, M., & Grillari, J. (2023). Senopathies-diseases associated with cellular senescence. Biomolecules13(6), 966. https://doi.org/10.3390/biom13060966
  7. Lushchak, O., Orru, M., Strilbytska, O., Berezovskyi, V., Cherkas, A., Storey, K. B., & Bayliak, M. (2023). Metabolic and immune dysfunctions in post-traumatic stress disorder: what can we learn from animal models?. EXCLI Journal, 22, 928–945. https://doi.org/10.17179/excli2023-6391
  8. Bayliak MM, Demianchuk OI, Gospodaryov DV, Balatskyi VA, Lushchak VI. Specific and combined effects of dietary ethanol and arginine on Drosophila melanogaster. Drug Chem Toxicol. 2023, 46:5, 895-905. https://doi.org/10.1080/01480545.2022.2105863
  9. Gospodaryov DV, Ballard JWO, Camus MF, DeSalle R, Garvin MR and Richter U (2023) Editorial: Energy-producing organelles and the nucleus: a phenomenal genomic friendship. Front. Genet. 14:1230032. doi: 10.3389/fgene.2023.1230032
  10. Giordano, L., Shvadchak, V. V., Arrupe, N., Lockhart, L. J. F., Sánchez, V. M., & Jovin, T. M. (2023). Tuning of environment-sensitive 3-hydroxychromone fluorophores based on strong donor substituents in positions 2 or 7. Dyes and Pigments218, 111479. https://doi.org/10.1016/j.dyepig.2023.111479
  11. Galkin, M., Topcheva, O., Priss, A., Borisova, T., & Shvadchak, V. V. (2023). Dopamine-induced oligomers of α-synuclein inhibit amyloid fibril growth and show no toxicity. ACS chemical neuroscience14(11), 2027–2034. https://doi.org/10.1021/acschemneuro.2c00815
  12. Dmytriv T.R., Tsiumpala S.A., Semchyshyn H.M., Storey K.B., Lushchak V.I. (2023) Mitochondrial dysfunction as a possible trigger of neuroinflammation at post-traumatic stress disorder (PTSD). Front. Physiol. 14:1222826. https://doi.org/10.3389/fphys.2023.1222826
  13. Lushchak, V. I., Covasa, M., Abrat, O. B., Mykytyn, T. V., Tverdokhlib, I. Z., Storey, K. B., Semchyshyn, H. (2023). Risks of obesity and diabetes development in the population of the Ivano-Frankivsk region in Ukraine. EXCLI Journal22, 1047–1054. https://doi.org/10.17179/excli2023-6296
  14. Galkin, M.Priss, A.Kyriukha, Y.Shvadchak, V. (2023) Navigating α-sSynuclein aggregation inhibition: methods, mechanisms, and molecular Targets. Chem. Rec. 2023, e202300282. https://doi.org/10.1002/tcr.202300282
  15. Kmita, H., Pinna, G., & Lushchak, V. I. (2023). Potential oxidative stress related targets of mitochondria-focused therapy of PTSD. Frontiers in physiology14, 1266575. https://doi.org/10.3389/fphys.2023.1266575
  16. Vatashchuk, M. V., Bayliak, M. M., Hurza, V. V., Demianchuk, O. I., Gospodaryov, D. V., & Lushchak, V. I. (2023). Alpha-ketoglutarate partially alleviates effects of high-fat high-fructose diet in mouse muscle. EXCLI Journal22, 1264–1277. https://doi.org/10.17179/excli2023-6608
  17. Danyliuk N., Lapchuk I., Kotsyubynsky V., Boychuk V., & Husak V. (2023). Effect of Mn2+ substitution on catalytic properties of Fe3-xMnxO4 nanoparticles synthesized via co-precipitation method. Physics and Chemistry of Solid State24(4), 748-760. https://doi.org/10.15330/pcss.24.4.748-760

Chapters of the monographs

  1. Lushchak, O., Gospodaryov, D., Strilbytska, O., Bayliak, M. (2023). Changing ROS, NAD and AMP: A path to longevity via mitochondrial therapeutics. In: Advances in Protein Chemistry and Structural Biology (Eds. U. Çakatay, M. CAN Atayik), Academic Press, 2023, pp. 157-197.  doi:10.1016/bs.apcsb.2023.03.005
  2. Vaiserman A.M.,  Lushchak O.V. Chapter 1 – Geroscience — the concept. In: Anti-Aging Pharmacology (Edited by V. K. Koltover). Academic Press, 2023, pp. 1-12. https://doi.org/10.1016/B978-0-12-823679-6.00004-7

  3. Vaiserman A.M.,  Lushchak O.V., Zayachkivska A., Koliada A.  Chapter 7 – Curcumin. In: Anti-Aging Pharmacology (Edited by V. K. Koltover). Academic Press, 2023, pp. 153-176. https://doi.org/10.1016/B978-0-12-823679-6.00014-X
  4.  Piskovatska V.,  Buheruk V.,  Strilbytska O.,  Zayachkivska A., Lushchak O. V. Chapter 10 – Nonsteroidal anti-inflammatory drugs. In: Anti-Aging Pharmacology (Edited by V. K. Koltover). Academic Press, 2023, pp. 227-243.https://doi.org/10.1016/B978-0-12-823679-6.00015-1
  5. Husak V., Bayliak M. Molecular mechanisms of chromium tolerance in plants: A key role of antioxidant defense. In: Kumar, N., Walther, C., Gupta, D.K. (eds) Chromium in plants and environment. Environmental Science and Engineering. Springer, Cham, 2023. pp. 443–479 https://doi.org/10.1007/978-3-031-44029-8_16

 Go to book series home page - Advances in Protein Chemistry and Structural Biology  Book cover

Publications indexed in SCOPUS

  1. Semaniuk, U. V., Gospodaryov, D. V., Strilbytska, O. M., Kucharska, A. Z., Sokół-Łętowska, A., Burdyliuk, N. I., Storey, K. B., Bayliak, M. M., & Lushchak, O. (2022). Chili-supplemented food decreases glutathione-S-transferase activity in Drosophila melanogaster females without a change in other parameters of antioxidant system. Redox report : communications in free radical research27(1), 221–229. https://doi.org/10.1080/13510002.2022.2123884
  2. Bayliak, M. M., Vatashchuk, M. V., Gospodaryov, D. V., Hurza, V. V., Demianchuk, O. I., Ivanochko, M. V., Burdyliuk, N. I., Storey, K. B., Lushchak, O., & Lushchak, V. I. (2022). High fat high fructose diet induces mild oxidative stress and reorganizes intermediary metabolism in male mouse liver: Alpha-ketoglutarate effects. Biochimica et biophysica acta. General subjects1866(12), 130226. https://doi.org/10.1016/j.bbagen.2022.130226
  3. Strilbytska O, Semaniuk U, Bubalo V, Storey KB, Lushchak O. Dietary Choice Reshapes Metabolism in Drosophila by Affecting Consumption of Macronutrients. Biomolecules. 2022; 12(9):1201. https://doi.org/10.3390/biom12091201
  4. Poryvai A., Galkin M., Shvadchak V., Slanina T. (2022). Red-Shifted Water-Soluble BODIPY Photocages for Visualisation and Controllable Cellular Delivery of Signaling Lipids. Angewandte Chemie (International ed. in English), e202205855. https://doi.org/10.1002/anie.202205855
  5. Gospodaryov D.V. Battlefields for research in Ukraine. Nat Aging 2, 367 (2022). https://doi.org/10.1038/s43587-022-00221-z
  6. Semaniuk U. V., Gospodaryov D. V., Strilbytska O. M., Kucharska A. Z., Sokół-Łętowska A., Burdyliuk N. I., Storey K. B., Bayliak M. M., Lushchak O. (2022). Chili pepper extends lifespan in a concentration-dependent manner and confers cold resistance on Drosophila melanogaster cohorts by influencing specific metabolic pathways. Food & function13(15), 8313–8328. https://doi.org/10.1039/d2fo00930g
  7. Bayliak MM, Sorochynska OM, Kuzniak OV, Drohomyretska IZ, Klonovskyi AY, Hrushchenko AO, Vatashchuk MV, Mosiichuk NM, Storey KB, Garaschuk O, Lushchak VI. High stability of blood parameters during mouse lifespan: sex-specific effects of every-other-day fasting. Biogerontology23(5), 559–570. https://doi.org/10.1007/s10522-022-09982-x
  8. Vatashchuk, M. V., Bayliak, M. M., Hurza, V. V., Storey, K. B., & Lushchak, V. I. (2022). Metabolic Syndrome: Lessons from Rodent and Drosophila Models. BioMed research international2022, 5850507. https://doi.org/10.1155/2022/5850507
  9. Strilbytska O., Semaniuk U., Burdyliuk N., & Lushchak O. (2022). Evaluation of biological effects of graphene oxide using Drosophila. Physics and Chemistry of Solid State23(2), 242-248. https://doi.org/10.15330/pcss.23.2.242-248
  10. Kuzniak, O. V., Sorochynska, O. M. ., Bayliak, M. M., Klonovskyi, A. Y., Vasylyk, Y. V., Semchyshyn, H. M., Storey, K. B., Garaschuk, O., & Lushchak, V. I. (2022). Feeding to satiation induces mild oxidative/carbonyl stress in the brain of young mice. EXCLI Journal21, 77-92. https://doi.org/10.17179/excli2021-4347
  11. Strilbytska, O. M., Tsiumpala, S. A., Kozachyshyn, I. I., Strutynska, T., Burdyliuk, N., Lushchak, V., & Lushchak, O. (2022). The effects of low-toxic herbicide Roundup and glyphosate on mitochondria. EXCLI Journal21, 183-196. https://doi.org/10.17179/excli2021-4478
  12. Bayliak, M. M., Gospodaryov, D. V., & Lushchak, V. I. (2022). Mimicking caloric restriction for anti-aging effects: the pro-oxidant role of alpha-ketoglutarate. Current Opinion in Toxicology, 30, 100339. https://doi.org/10.1016/j.cotox.2022.02.012
  13. Strilbytska OM, Semaniuk UV, Strutynska TR, Burdyliuk NI, Tsiumpala S, Bubalo V, Lushchak O. Herbicide Roundup shows toxic effects in nontarget organism Drosophila. Arch Insect Biochem Physiol. 2022 Apr 6:e21893. https://doi.org/10.1002/arch.21893
  14. Kuzub N, Smialkovska V, Momot V, Moseiko V, Lushchak O, Koliada A. Evaluation of Epigenetic Age Based on DNA Methylation Analysis of Several CpG Sites in Ukrainian Population. Front Genet. 2022;12:772298. https://doi.org/10.3389/fgene.2021.772298
  15. Husak, V., Strutynska, T., Burdyliuk, N., Pitukh, A., Bubalo, V., Falsfushynska, H., Strilbytska, O., & Lushchak, O. (2022). Low-toxic herbicides Roundup and Atrazine disturb free radical processes in Daphnia in environmentally relevant concentrations. EXCLI Journal21, 595-609. https://doi.org/10.17179/excli2022-4690
  16. Lenzen, S., Lushchak, V.I. & Scholz, F. The pro-radical hydrogen peroxide as a stable hydroxyl radical distributor: lessons from pancreatic beta cells. Arch Toxicol. 2022, 96, 1915–1920. https://doi.org/10.1007/s00204-022-03282-6
  17. Falfushynska, H., Khatib, I., Kasianchuk, N., Lushchak, O., Horyn, O., & Sokolova, I. M. (2022). Toxic effects and mechanisms of common pesticides (Roundup and chlorpyrifos) and their mixtures in a zebrafish model (Danio rerio). Science of The Total Environment, 823: 155236. https://doi.org/10.1016/j.scitotenv.2022.155236
  18. Strilbytska, O. M., Semaniuk, U. V., Burdyliuk, N. I., & Lushchak, O. V. (2022). Protein content in the parental diet affects cold tolerance and antioxidant system state in the offspring Drosophila. Ukrainian Biochemical Journal, 94(1), 86-94. https://doi.org/10.15407/ubj94.01.086
  19. Strilbytska, O. M., Semaniuk, U. V., Burdyliyk, N. I., Bubalo, V., & Lushchak, O. V. (2022). Developmental diet defines metabolic traits in larvae and adult Drosophila. Ukrainian Biochemical Journal, 94(1), 53-63. https://doi.org/10.15407/ubj94.01.053
  20. Strilbytska, Olha, Strutynska, Tetiana, Semaniuk, Uliana, Burdyliyk, Nadia, Bubalo, Volodymyr, & Lushchak, Oleh. (2022). Dietary Sucrose Determines Stress Resistance, Oxidative Damages, and Antioxidant Defense System in Drosophila. Scientifica, 2022, 7262342. https://doi.org/10.1155/2022/7262342
  21. Falfushynska, H., Lushchak, O., & Siemens, E. (2022). The Application of Multivariate Statistical Methods in Ecotoxicology and Environmental Biochemistry. Paper presented at the Proceedings of International Conference on Applied Innovation in IT.
Монографії та розділи книг  
Lushchak V.I. (2022) Redox Dynamic Homeostasis and Aging. In: Çakatay U. (eds) Redox Signaling and Biomarkers in Ageing. Healthy Ageing and Longevity, vol 15. Springer, Cham. https://doi.org/10.1007/978-3-030-84965-8_1

Publications indexed in SCOPUS

  1. Strilbytska O. M.  Stefanyshyn N. P., Semaniuk U. V., Lushchak O. V. Yeast concentration in the diet defines Drosophila metabolism of both parental and offspring generations. Ukr.Biochem. J. 2021; Volume 93, Issue 6, Nov-Dec, pp. 119-129. doi: https://doi.org/10.15407/ubj93.06.119
  2. Strilbytska1 O., Zayachkivska A., Strutynska, T., Semaniuk U., Vaiserman A., Lushchak O. Dietary protein defines stress resistance, oxidative damages and antioxidant defense system in Drosophila melanogaster. Ukr.Biochem.J. 2021; Volume 93, Issue 5, Sep-Oct, pp. 90-101. doi: https://doi.org/10.15407/ubj93.05.090
  3. Mykhailovych V, Kanak A, Cojocaru Ş, Chitoiu-Arsene E-D, Palamaru MN, Iordan A-R, Korovyanko O, Diaconu A, Ciobanu VG, Caruntu G, Lushchak O, Fochuk P, Khalavka Y, Rotaru A. Structural, Optical, and Catalytic Properties of MgCr2O4 Spinel-Type Nanostructures Synthesized by Sol–Gel Auto-Combustion Method. Catalysts. 2021; 11(12):1476. https://doi.org/10.3390/catal11121476
  4. Galkin M, Priss A, Topcheva O, Yushchenko DA, Shvadchak VV. FRET-based assay for intracellular evaluation of α-synuclein aggregation inhibitors. J Neurochem. 2021;159(5):901-912.https://doi.org/10.1111/jnc.15528
  5. Lushchak VI, Duszenko M, Gospodaryov DV, Garaschuk O. Oxidative Stress and Energy Metabolism in the Brain: Midlife as a Turning Point. Antioxidants. 2021; 10(11):1715. https://doi.org/10.3390/antiox10111715
  6. Vaiserman A,  Lushchak O. DNA methylation changes induced by prenatal toxic metal exposure: An overview of epidemiological evidence. Environmental Epigenetics, Volume 7, Issue 1, 2021, dvab007, https://doi.org/10.1093/eep/dvab007
  7. Lushchak VI, Lushchak O. Interplay between reactive oxygen and nitrogen species in living organisms. Chem Biol Interact. 2021 Oct 1;349:109680. doi: 10.1016/j.cbi.2021.109680.
  8. Kamyshnyi O, Matskevych V, Lenchuk T, Strilbytska O, Storey K, Lushchak O. Metformin to decrease COVID-19 severity and mortality: Molecular mechanisms and therapeutic potential. Biomed Pharmacother. 2021 Oct 6;144:112230. doi: 10.1016/j.biopha.2021.112230.
  9. Peteliuk V., Rybchuk L., Bayliak M., Storey K. B. & Lushchak, O. (2021). Natural sweetener Stevia rebaudiana: Functionalities, health benefits and potential risks. EXCLI Journal, 20, 1412-1430. https://doi.org/10.17179/excli2021-4211
  10. Bayliak, M. M., Dmytriv, T. R., Melnychuk, A. V., Strilets, N. V., Storey , K. B., & Lushchak, V. I. (2021). Chamomile as a potential remedy for obesity and metabolic syndrome. EXCLI Journal, 20, 1261-1286. https://doi.org/10.17179/excli2021-4013
  11. Strilbytska OM, Strutynska TR,  Semaniuk UV, Burdyliuk NI,  Storey KB,  Lushchak OV (2021). Parental dietary sucrose affects metabolic and antioxidant enzyme activities in Drosophila. Entomological Science  https://doi.org/10.1111/ens.12479
  12. Lushchak, V. I.,  Storey, K. B. (2021). Oxidative stress concept updated: Definitions, classifications, and regulatory pathways implicated . EXCLI Journal, 20, 956-967. https://doi.org/10.17179/excli2021-3596
  13. Semaniuk U, Strilbytska O, Malinovska K, Storey KB, Vaiserman A, Lushchak V, Lushchak O. (2021) Factors that regulate expression patterns of insulin-like peptides and their association with physiological and metabolic traits in Drosophila. Insect Biochem Mol Biol. 135:103609. https://doi.org/10.1016/j.ibmb.2021.103609
  14. Koliada, A., Moseiko, V., Romanenko, M., Lushchak, O., Kryzhanovska, N., Guryanov, V., Vaiserman, A. (2021). Sex differences in the phylum‐level human gut microbiota composition. BMC microbiology, 21(1), 1-9.https://doi.org/10.1186/s12866-021-02198-y
  15. Vaiserman, A., Koliada, A., Lushchak, O. (2021). Phyto-nanotechnology in anti-aging medicine. Aging (Albany NY), 13(8), 10818. https://doi.org/10.18632/aging.203026
  16. Semaniuk, U., Gospodaryov, D., Mishchanyn, K., Storey, K., & Lushchak, O. (2021). Drosophila insulin-like peptides regulate concentration-dependent changes of appetite to different carbohydrates. Zoology (Jena, Germany), 146, 125927. Advance online publication. https://doi.org/10.1016/j.zool.2021.125927
  17. Vaiserman, A., Koliada, A., Lushchak, O., Castillo, M. J. (2021). Repurposing drugs to fight aging: The difficult path from bench to bedside. Medicinal research reviews, 41(3), 1676–1700. https://doi.org/10.1002/med.21773
  18. Semaniuk, U., Gospodaryov, D., Mishchanyn, K., Storey, K., & Lushchak, O. (2021). Drosophila insulin-like peptides regulate concentration-dependent changes of appetite to different carbohydrates. Zoology (Jena, Germany), 146, 125927. Advance online publication. https://doi.org/10.1016/j.zool.2021.125927
  19. Heier, C., Klishch, S., Stilbytska, O., Semaiuk, U., & Lushchak, O. (2021). The Drosophila model to interrogate triacylglycerol biology. Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids, 158924. https://doi.org/10.1016/j.bbalip.2021.158924
  20. Bayliak, M. M., Mosiichuk, N. M., Sorochynska, O. M., Kuzniak, O. V., Sishchuk, L. O., Hrushchenko, A. O., Semchuk, A. O., Pryimak, T. V., Vasylyk, Y. V., Gospodaryov, D. V., Storey, K. B., Garaschuk, O., & Lushchak, V. I. (2021).  Middle aged turn point in parameters of oxidative stress and glucose catabolism in mouse cerebellum during lifespan: minor effects of every-other-day fasting. Biogerontology. 22, 315–328. https://doi.org/10.1007/s10522-021-09918-x
  21. Sorochynska, O. M., Kuzniak, O. V., Bayliak, M. M., Vasylyk, Y. V., Storey, K. B., Lushchak, V. I. (2021). Every-other-day fasting reduces glycolytic capability in the skeletal muscle of young mice. Biologia, 76, 1627–1634. https://doi.org/10.1007/s00424-021-02529-y
  22. Lushchak, V.I. (2021) Interplay between bioenergetics and oxidative stress at normal brain aging. Aging as a result of increasing disbalance in the system oxidative stress–energy provision. Pflugers Arch – Eur J Physiol. 473, 713–722. https://doi.org/10.1007/s00424-021-02531-4
  23. Semchyshyn, H. (2021) Is carbonyl/AGE/RAGE stress a hallmark of the brain aging?. Pflugers Arch – Eur J Physiol. 473, 723–734. https://doi.org/10.1007/s00424-021-02529-y
  24. Semaniuk, U., Piskovatska, V., Strilbytska, O., Strutynska, T., Burdyliuk, N., Vaiserman, A., Bubalo V., Storey K.B. & Lushchak, O. (2021). Drosophila insulin‐like peptides: from expression to functions–a review. Entomologia Experimentalis et Applicata. 169 (2). 195-208. https://doi.org/10.1111/eea.12981
  25. Bayliak MM, Sorochynska OM, Kuzniak OV, Gospodaryov DV, Demianchuk OI, Vasylyk YV, Mosiichuk NM, Storey KB, Garaschuk O, Lushchak VI. (2021). Middle age as a turning point in mouse cerebral cortex energy and redox metabolism: Modulation by every-other-day fasting. Experimental Gerontology, Vol. 145, 111182. https://doi.org/10.1016/j.exger.2020.111182
  26. Bayliak, M. M., Lushchak, V. I. (2021). Pleiotropic effects of alpha-ketoglutarate as a potential anti-ageing agent. Ageing Research Reviews, 101237. https://doi.org/10.1016/j.arr.2020.101237
  27. Nataliia Petriv, Lavinia Neubert, Myroslava Vatashchuk, Kai Timrott, Huizhen Suo, Inga Hochnadel, René Huber, Christina Petzold, Anastasiia Hrushchenko, Andriy S. Yatsenko, Halyna R. Shcherbata, Heiner Wedemeyer, Ralf Lichtinghagen, Halina Falfushynska, Volodymyr Lushchak, Michael P. Manns, Heike Bantel, Halyna Semchyshyn & Tetyana Yevsa (2021) Increase of α-dicarbonyls in liver and receptor for advanced glycation end products on immune cells are linked to nonalcoholic fatty liver disease and liver cancer, OncoImmunology, 10:1, DOI: 10.1080/2162402X.2021.1874159

Books and book chapters

Lushchak, O., Piskovatska, V., Strilbytska, O., Kindrat, I., Stefanyshyn, N., Koliada, A., … & Vaiserman, A. (2021).  Aspirin as a Potential Geroprotector: Experimental Data and Clinical Evidence. In: Guest P.C. (eds) Reviews on New Drug Targets in Age-Related Disorders. Advances in Experimental Medicine and Biology, vol 1286. Springer, Cham, 145-161. https://doi.org/10.1007/978-3-030-55035-6_11
 Vaiserman A,  Lushchak O, Koliada A,
Chapter 2 – Environmental epigenetic epidemiology,
Editor(s): Trygve O. Tollefsbol, In Translational Epigenetics,
Medical Epigenetics (Second Edition), Academic Press, Volume 29, 2021,
Pages 11-31,
ISBN 9780128239285,


Publications indexed in SCOPUS

  1. Gospodaryov, D.V., Strilbytska, O.M., Semaniuk, U.V., Perkhulyn N.V., Rovenko B.M., Yurkevych I.S., Barata A.G., Dick T.P., Lushchak O.V., Jacobs H.T. Alternative NADH dehydrogenase extends lifespan and increases resistance to xenobiotics in Drosophila. Biogerontology. 2020. 21, 155-171 https://doi.org/10.1007/s10522-019-09849-8
  2. Lushchak, O., Strilbytska, O., Koliada, A., Zayachkivska, A., Burdyliuk, N., Yurkevych, I., Storey, K. B., & Vaiserman, A. (2020). Nanodelivery of phytobioactive compounds for treating aging-associated disorders. GeroScience42(1), 117–139. https://doi.org/10.1007/s11357-019-00116-9
  3. Lushchak O, Koliada A, Zayachkivska A,Vaiserman A. Nanodelivery of Natural Antioxidants: An Anti-aging Perspective. Front. Bioeng. Biotechnol., 10 January 2020 | https://doi.org/10.3389/fbioe.2019.00447
  4. Strilbytska, O., Velianyk, V., Burdyliuk, N., Yurkevych, I. S., Vaiserman, A., Storey, K. B., Pospisilik, A., & Lushchak, O. (2020). Parental dietary protein-to-carbohydrate ratio affects offspring lifespan and metabolism in Drosophila. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology241, 110622. https://doi.org/10.1016/j.cbpa.2019.110622
  5. Strilbytska, O. M., Storey, K. B., & Lushchak, O. V. (2020). TOR signaling inhibition in intestinal stem and progenitor cells affects physiology and metabolism in DrosophilaComparative biochemistry and physiology. Part B, Biochemistry & molecular biology243-244, 110424. https://doi.org/10.1016/j.cbpb.2020.110424
  6. Semchyshyn H. Reactive Carbonyls Induce TOR- And Carbohydrate-Dependent Hormetic Response in Yeast. Scientific World Journal. Volume 2020, 2020, Article number 4275194. https://doi.org/10.1155/2020/4275194
  7. Koliada, A., Gavrilyuk, K., Burdylyuk, N., Strilbytska, O., Storey, K. B., Kuharskii, V., Lushchak, O., & Vaiserman, A. (2020). Mating status affects Drosophila lifespan, metabolism and antioxidant system. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology246, 110716. https://doi.org/10.1016/j.cbpa.2020.110716
  8. Koliada A, Moseiko V, Romanenko M, Piven L, Lushchak O, Kryzhanovska N, Guryanov V, Vaiserman A. Seasonal variation in gut microbiota composition: cross-sectional evidence from Ukrainian population. BMC Microbiol. 2020, 20(1):100 https://doi.org/10.1186/s12866-020-01786-8
  9. Vaiserman A, Koliada A, Lushchak O. Neuroinflammation in pathogenesis of Alzheimer’s disease: Phytochemicals as potential therapeutics. Mech Ageing Dev. 2020;189:111259. https://doi.org/10.1016/j.mad.2020.111259
  10. Bulyhina TV, Zdorovenko EL, Varbanets LD, Shashkov AS, Kadykova AA, Knirel YA, Lushchak OV. Structure of O-Polysaccharide and Lipid A of Pantoea Agglomerans 8488. Biomolecules. 2020,10(5):804. https://doi.org/10.3390/biom10050804
  11. Bayliak MM, Demianchuk OI, Gospodaryov DV, Abrat OB, Lylyk MP, Storey KB, Lushchak VI. Mutations in genes cnc or dKeap1 modulate stress resistance and metabolic processes in Drosophila melanogaster. Comp Biochem Physiol A Mol Integr Physiol. 2020, 248:110746. https://doi.org/10.1016/j.cbpa.2020.110746
  12. Yurkevych IS, Gray LJ, Gospodaryov DV, Burdylyuk NI, Storey KB, Simpson SJ, Lushchak O. Development of fly tolerance to consuming a high-protein diet requires physiological, metabolic and transcriptional changes. Biogerontology. 2020, 21(5):619-636. https://doi.org/10.1007/s10522-020-09880-0
  13. Piskovatska V, Storey KB, Vaiserman AM, Lushchak O. The use of metformin to increase the human healthspan. Adv Exp Med Biol. 2020;1260:319-332.https://doi.org/10.1007/978-3-030-42667-5_13
  14. Vaiserman A, Romanenko M, Piven L, Moseiko V, Lushchak O, Kryzhanovska N, Guryanov V, Koliada A. Differences in the gut Firmicutes to Bacteroidetes ratio across age groups in healthy Ukrainian population. BMC Microbiol. 2020, 20(1):221. https://doi.org/10.1186/s12866-020-01903-7
  15. Vaiserman, A., Koliada, A., Zayachkivska, A., & Lushchak, O. (2020). Curcumin: A therapeutic potential in ageing-related disorders. PharmaNutrition, 100226. https://doi.org/10.1016/j.phanu.2020.100226
  16. Husak, V. H., Vasyliuk, D. V., Shcherba, R. M., & Lushchak, V. I. (2020). Effect of light emitted by diodes on growth and pigment content of black currant plantlets in vitro. Agriculturae Conspectus Scientificus85(4), 317-323. https://acs.agr.hr/acs/index.php/acs/article/view/1781
  17. Kamyshnyi, A., Krynytska, I., Matskevych, V., Marushchak, M., & Lushchak, O. (2020). Arterial Hypertension as a Risk Comorbidity Associated with COVID-19 Pathology. International Journal of Hypertension2020https://www.hindawi.com/journals/ijhy/2020/8019360/
  18. Strilbytska, O. M., Zayachkivska, A., Koliada, A., Galeotti, F., Volpi, N., Storey, K. B., Vaiserman A. & Lushchak, O. (2020). Anise hyssop Agastache foeniculum increases lifespan, stress resistance and metabolism by affecting free radical processes in Drosophila. Frontiers in Physiology11, 1669.https://www.frontiersin.org/articles/10.3389/fphys.2020.596729/full
  19. Pierzynowska, K., Deshpande, A., Mosiichuk, N., Terkeltaub, R., Szczurek, P., Salido, E., Pierzynowski, S., & Grujic, D. (2020). Oral Treatment With an Engineered Uricase, ALLN-346, Reduces Hyperuricemia, and Uricosuria in Urate Oxidase-Deficient Mice. Frontiers in medicine7, 569215. https://doi.org/10.3389/fmed.2020.569215
  20. Strilbytska, O. M., Semaniuk, U. V., Storey, K. B., Yurkevych, I. S., & Lushchak, O. (2020). Insulin Signaling in Intestinal Stem and Progenitor Cells as an Important Determinant of Physiological and Metabolic Traits in DrosophilaCells9(4), 803.https://doi.org/10.3390/cells9040803
  21. Michels, B., Gerber, B., Wessjohann, L., Franke, K., Sigrist, S., Bhukel, A., Lushchak O., … & Song, I. (2020). U.S. Patent Application No. 16/766,696.


  1. Stambulska U.Y., Bayliak M.M. (2020) Legume-Rhizobium Symbiosis: Secondary Metabolites, Free Radical Processes, and Effects of Heavy Metals. In: Merillon JM., Ramawat K. (eds) Co-Evolution of Secondary Metabolites. Reference Series in Phytochemistry. Springer, Cham. 291-322. https://doi.org/10.1007/978-3-319-76887-8_43-1
  2. Piskovatska V., Storey K.B., Vaiserman A.M., Lushchak O. (2020) The Use of Metformin to Increase the Human Healthspan. In: Guest P. (eds) Reviews on New Drug Targets in Age-Related Disorders. Advances in Experimental Medicine and Biology, vol 1260. Springer, Cham.https://doi.org/10.1007/978-3-030-42667-5_13
  3. Bayliak M.M., Abrat O.B. (2020) Role of Nrf2 in Oxidative and Inflammatory Processes in Obesity and Metabolic Diseases. In: Deng H. (eds) Nrf2 and its Modulation in Inflammation. Progress in Inflammation Research, vol 85. Springer, Cham. https://doi.org/10.1007/978-3-030-44599-7_7
  4. Lushchak O., Karpenko R., Zayahckivska A., Koliada A., Vaiserman A. (2020) Lipid-Based Nano-delivery of Phytobioactive Compounds in Anti-aging Medicine. In: Lai WF. (eds) Systemic Delivery Technologies in Anti-Aging Medicine: Methods and Applications. Healthy Ageing and Longevity, vol 13. Springer, Cham. https://doi.org/10.1007/978-3-030-54490-4_8
  5. Vaiserman A., Lushchak O. (2020) Health and Pro-Longevity Interventions. In: Sholl J., Rattan S.I. (eds) Explaining Health Across the Sciences. Healthy Ageing and Longevity, vol 12. Springer, Cham. https://doi.org/10.1007/978-3-030-52663-4_27

Publications indexed in SCOPUS

  1. Bayliak, M. M., Abrat, O. B., Storey, J. M., Storey, K. B., & Lushchak, V. I. (2019). Interplay between diet-induced obesity and oxidative stress: Comparison between Drosophila and mammalsComparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 228, 18-12
  2. Bayliak, M. M., Lylyk, M. P., Gospodaryov, D. V., Kotsyubynsky, V. O., Butenko, N. V., Storey, K. B., & Lushchak, V. I. (2019). Protective effects of alpha-ketoglutarate against aluminum toxicity in Drosophila melanogasterComparative Biochemistry and Physiology Part C: Toxicology & Pharmacology217, 41-53.
  3. Piskovatska, V., Stefanyshyn, N., Storey, K. B., Vaiserman, A. M., & Lushchak, O. (2019). Metformin as geroprotector: experimental and clinical evidenceBiogerontology. 20(1), 33-48.
  4. Lushchak, O., Strilbytska, O. M., Yurkevych, I., Vaiserman, A. M., & Storey, K. B. (2019). Implications of amino acid sensing and dietary protein to the aging processExperimental gerontology. 115, 69-78.
  5. McDonald A.E.Gospodaryov D.V. (2019) Alternative NAD(P)H dehydrogenase and alternative oxidase: Proposed physiological roles in animals.  Mitochondrion. 45, 107-117.
  6. Sorochynska, O.M., Bayliak, M.M., Vasylyk, Y.V., Kuzniak, O.V., Drohomyretska, I.Z., Klonovskyi, A.Y., Storey, J.M., Storey, K.B., Lushchak, V.I. (2019). Intermittent fasting causes metabolic stress and leucopenia in young mice. Ukr. Biochem. J. 91(1), 53-64.
  7. Lushchak, O.V., Karaman, H.S., Kozeretska, I.A., Koliada A.K., Zabuga O.G., Pisaruk A.V., Koshel N.M., Mechova L.V., Inomistova M.V., Khranovska N.M., Vaiserman A.M. (2019) Larval crowding results in hormesis-like effects on longevity in Drosophila: timing of eclosion as a model. Biogerontology. 20: 191. https://doi.org/10.1007/s10522-018-9786-0
  8. Vaiserman V., Lushchak O. Prenatal malnutrition-induced epigenetic dysregulation as a risk factor for type 2 diabetes. International Journal of Genomics, vol. 2019, Article ID 3821409, 11 pages, 2019. https://doi.org/10.1155/2019/3821409.
  9. Vaiserman A, Lushchak O. Developmental origins of type 2 diabetes: Focus on epigenetics. Ageing Res Rev. 2019, 55:100957. doi: 10.1016/j.arr.2019.100957.
  10. Vitalina Bashynska, Alexander Koliada, Kateryna Murlanova, Oksana Zahorodnia, Yuliia Borysovych, Vladyslav Moseiko, Oleh Lushchak, and Alexander Vaiserman., “Prevalence of Some Genetic Risk Factors for Nicotine Dependence in Ukraine,” Genetics Research International, vol. 2019, Article ID 2483270, 8 pages, 2019. https://doi.org/10.1155/2019/2483270.
  11. Gubina N, Naudi A, Stefanatos R, Jove M, Scialo F, Fernandez-Ayala DJ,Rantapero T, Yurkevych I, Portero-Otin M,
    Nykter M, Lushchak O, Navas P, Pamplona R, Sanz A. Essential Physiological Differences Characterize Short- and Long-Lived Strains of Drosophila melanogaster. J Gerontol A Biol Sci Med Sci. 2019 Nov 13;74(12):1835-1843. doi: 10.1093/gerona/gly143.
  12. Sorochynska OM, Bayliak MM, Gospodaryov DV, Vasylyk YV, Kuzniak OV, Pankiv TM, Garaschuk O, Storey KB and Lushchak VI (2019) Every-Other-Day Feeding Decreases Glycolytic and Mitochondrial Energy-Producing Potentials in the Brain and Liver of Young MiceFront. Physiol. 10:1432. doi: 10.3389/fphys.2019.01432


  1. Piskovatska V., Strilbytska O., Koliada A., Vaiserman A., Lushchak O. (2019) Health Benefits of Anti-aging Drugs. In: Harris J., Korolchuk V. (eds) Biochemistry and Cell Biology of Ageing: Part II Clinical Science. Subcellular Biochemistry, vol 91. Springer, Singapore (SCOPUS)
  2. Vaiserman A., Lushchak O. (2019). Early-Life Adjustment of Epigenetic Aging Clock. In: Vaiserman O. Early Life Origins of Ageing and Longevity. Springer, P. 269-282.
  3. Encyclopedia of Biomedical Gerontology. 1st Edition. Ed. by S. Rattan.1640 pp.

Publications indexed in SCOPUS

1. Garaschuk O.Semchyshyn H.M.Lushchak V.IHealthy brain aging: Interplay between reactive species, inflammation and energy supply.  Ageing Research Reviews. Volume 43, 2018, Pages 26-45

2. Abrat O.B.Storey J.M.Storey K.B.Lushchak V.I. High amylose starch consumption induces obesity in Drosophila melanogaster and metformin partially prevents accumulation of storage lipids and shortens lifespan of the insects. Comparative Biochemistry and Physiology -Part A : Molecular and Integrative Physiology. Volume 215, 2018, Pages 55-62

3. Bayliak M.M., Hrynkiv O.V., Knyhynytska R.V., Lushchak V.I. Alpha-ketoglutarate enhances freeze–thaw tolerance and prevents carbohydrate-induced cell death of the yeast Saccharomyces cerevisiaeArchives of Microbiology. Volume 200, Issue 1, 2018, Pages 33-46

4. Bayliak M.M., Lylyk M.P., Maniukh O.V., Storey J.M.Storey K.B.Lushchak V.I. Dietary l-arginine accelerates pupation and promotes high protein levels but induces oxidative stress and reduces fecundity and life span in Drosophila melanogaster. Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology. Volume 188, Issue 1, 2018, Pages 37-55

5. Semaniuk U., Feden’ko Kh., Yurkevych I.S., Storey K.B., Simpson S.J., Lushchak O. Within-diet variation in rates of macronutrient consumption and reproduction does not accompany changes in lifespan in Drosophila melanogaster. Entomologia Experimentalis et Applicata. Volume 166, Issue 1, 2018, Pages 74-80

7. Nuzhyna, N.Baglay, K.Golubenko, A.Lushchak, O.  Anatomically distinct representatives of Cactaceae Juss. family have different response to acute heat shock stress. Flora: Morphology, Distribution, Functional Ecology of Plants. Volume 242, 2018, Pages 137-145

8. Husak, V.V., Mosiichuk, N.M., Kubrak, O.I., Matviishyn, T.M., Storey, J.M., Storey, K.B., Lushchak, V.I. Acute exposure to copper induces variable intensity of oxidative stress in goldfish tissues (2018) Fish Physiology and Biochemistry, 44 (3), pp. 841-852.

9. Stambulska U., Bayliak M.M., Lushchak V.I. Chromium(VI) toxicity in legume plants: modulation effects of rhizobial symbiosis. BioMed Research International. 2018. Vol. 2018, Article ID 8031213, 13 pages. doi:10.1155/2018/8031213

10. Lushchak O.,  Zayachkivska A., Vaiserman A., “Metallic Nanoantioxidants as Potential Therapeutics for Type 2 Diabetes: A Hypothetical Background and Translational Perspectives,” Oxidative Medicine and Cellular Longevity, vol. 2018, Article ID 3407375, 9 pages, 2018. https://doi.org/10.1155/2018/3407375

11. Vaiserman A., Koliada A., Lushchak O. Developmental programming of aging trajectory. Ageing Res Rev. 2018, 47:105-122.

12.  Semaniuk U.V., Gospodaryov D.V., Feden’ko K.M., Yurkevych I.S., Vaiserman A.M., Storey K.B., Simpson S.J., Lushchak O. Insulin-Like Peptides Regulate Feeding Preference and Metabolism in Drosophila. Front Physiol. 2018, 9:1083. doi: 10.3389/fphys.

13. Michels, B., Zwaka, H., Bartels, R., Lushchak, O., Franke, K., Endres, T., … Gerber, B. (2018). Memory enhancement by ferulic acid ester across species. Science Advances, 4(10). https://doi.org/10.1126/sciadv.aat6994

14. Lushchak, V. I., Matviishyn, T. M., Husak, V. V., Storey, J. M., & Storey, K. B. (2018). Pesticide toxicity: a mechanistic approachEXCLI journal17, 1101-1136. doi:10.17179/excli2018-1710

15. Lylyk M.P. , Bayliak M. M., Shmihel H. V., StoreyJ. M. , Storey K.B., Lushchak V. I. Effects of alpha-ketoglutarate on lifespan and functional aging of Drosophila melanogaster flies. Ukr.Biochem.J. 2018. Vol. 90 (6), 49-61



Lushchak O., Vaiserman A., Koliada A. Epigenetic Programming of Human Disease and Aging. In: Еpigenetics in human disease. Second edition. Translational Epigenetics Series. Volume 6” . Ed. Trygve O. Tollefsbol. Academic Press, 2018. Chapter 32. pp. 975-994.


Publications indexed in SCOPUS

1. Perkhulyn, N.V., Rovenko, B.M., Lushchak, O.V., Storey, J.M., Storey, K.B., Lushchak, V.I. Exposure to sodium molybdate results in mild oxidative stress in Drosophila melanogaster. Redox Report. Volume 22, Issue 3, 4 May 2017, Pages 137-146

2. Husak, V.V., Mosiichuk, N.M., Storey, J.M., Storey, K.B., Lushchak, V.I.  Acute exposure to the penconazole-containing fungicide Topas partially augments antioxidant potential in goldfish tissues. Comparative Biochemistry and Physiology Part – C: Toxicology and PharmacologyVolume 193, 1 March 2017, Pages 1-8

5. Burdyliuk, N., Bayliak, M. Effects of Long-Term Cultivation on Medium with Alpha-Ketoglutarate Supplementation on Metabolic Processes of Saccharomyces cerevisiae. Journal of Aging Research.Volume 2017, 2017, Article number 8754879

6. Lushchak, O., Strilbytska, O., Piskovatska, V., Storey, K.B., Koliada, A., Vaiserman, A.The role of the TOR pathway in mediating the link between nutrition and longevity. Mechanisms of Ageing and Development,(2017) 164, pp. 127-138.7.

7. Bayliak, M.M., Lylyk, M.P., Sorochynska, O.M.  Dietary alpha-ketoglutarate partially prevents age-related decline in locomotor activity and cold tolerance in Drosophila melanogaster. (2017) Biologia (Poland), 72 (4), pp. 458-467.

8. Strilbytska, O.M., Semaniuk, U.V., Storey, K.B., Edgar, B.A., Lushchak, O.V. Activation of the Tor/Myc signaling axis in intestinal stem and progenitor cells affects longevity, stress resistance and metabolism in Drosophila. (2017) Comparative Biochemistry and Physiology Part – B: Biochemistry and Molecular Biology, 203, pp. 92-99.

9. Koliada, A., Syzenko, G., Moseiko, V., Budovska, L., Puchkov, K., Perederiy, V., Gavalko, Y.,
Dorofeyev, A., Romanenko, M., Tkach, S., Sineok, L., Lushchak, O., Vaiserman, A. Association between body mass index and Firmicutes/Bacteroidetes ratio in an adult Ukrainian population (2017) BMC Microbiology, 17 (1), art. no. 120

10. Strilbytska, O.M., Koliada, A.K., Storey, K.B., Mudra, O., Vaiserman, A.M., Lushchak, O. Longevity and stress resistance are affected by activation of TOR/Myc in progenitor cells of Drosophila gut (2017) Open Life Sciences, 12 (1), pp. 429-442.
11. Vaiserman, A., Lushchak, O. Implementation of longevity-promoting supplements and medications in public health practice: Achievements, challenges and future perspectives (2017) Journal of Translational Medicine, 15 (1), art. no. 160




1. Vaiserman, A.M., Lushchak, O.V. Anti-Aging Drugs: Where are We and Where are We Going?
(2017) RSC Drug Discovery Series, 2017-January (57), DOI: 10.1039/9781782626602-00001

2. Lushchak, O., Gospodaryov, D.  Mimetics of Caloric Restriction(2017) RSC Drug Discovery Series, 2017-January (57). DOI: 10.1039/9781782626602-00229






2. Semchyshyn H.”Is part of the fructose effects on health related to increased AGE formation?”In: Dietary AGEs and Their Role In Health and Disease (ed J. Uribarri). CRC Press, 2017. Chapter 8.