50 Articles H-index 25
Times cited 1415, Without self-citations 1284
2023
Giordano, L., Shvadchak, V. V.,Arrupe, N., Falomir Lockhart, L. J., Sánchez, V. M., Jovin, T. M. (2023) Tuning of environment-sensitive 3-hydroxychromone fluorophores based on strong donor substituents in positions 2 or 7. Dyes and Pigments, 218, 111479
Galkin, M., Topcheva, O., Priss, A, Borisova, T., Shvadchak, V. V. (2023) Dopamine-Induced Oligomers of α-Synuclein Inhibit Amyloid Fibril Growth and Show No Toxicity. ACS Chem Neurosci, 14 (11), 2027-2034.
2022
Poryvai, A., Galkin, M., Shvadchak, V., Slanina, T. (2022) Red-shifted water-soluble BODIPY photocages for visualisation and controllable cellular delivery of signaling lipids, Angew. Chem. doi: 10.1002/anie.202205855
2021
Galkin, M., Priss, A., Topcheva, O., Yushchenko, D. A. and Shvadchak, V. V. (2021) FRET-based assay for intracellular evaluation of α-synuclein aggregation inhibitors, J Neurochem, 159, 901-12
Kurochka, A. S., Yushchenko, D. A., Bour, P., Shvadchak, V. V. (2021) Influence of lipid membranes on α synuclein aggregation, ACS Chem Neurosci, 12, 825-830.
Priss, A., Afitska, K., Galkin, M., Yushchenko, D. A., Shvadchak, V. V., (2021) Rationally designed protein-based inhibitor of α-synuclein fibrillization in cells, J Med Chem, 64, 6827-6837
Gaur, P., Galkin, M., Kurochka, A.,Ghosh, S.,Yushchenko, D. A., Shvadchak, V. V., (2021) Fluorescent probe for selective imaging of α-synuclein fibrils in living cells, ACS Chem Neurosci, 12 , 1293-1298
2020
Afitska, K., Priss, A., Yushchenko, D. A., Shvadchak, V. V. (2020) Structural optimization of inhibitors of α synuclein fibril growth: affinity to the fibril end as a crucial factor, J Mol Biol 432, 967-977.
Gaur, P., Galkin, M., Hauke, S., Redkin, R., Barnes, C., Shvadchak, V. V., Yushchenko, D. A. (2020). Reversible spatial and temporal control of lipid signaling. Chem Commun (Camb), 56, 10646-10649.
Sysoiev, D., Prochazkova, E., Semenenko, A., Pohl, R., Shishkina, S., Klepetarova, B., Shvadchak, V, Yushchenko, D. A. (2020). Di(benzothienyl)cyclobutenes: toward strained photoswitchable fluorophores. ChemPlusChem, 85, 2084-2092.
2019
Kyriukha, Y.A., Afitska, K., Kurochka, A.S., Sachan, S., Galkin, M., Yushchenko, D.A., Shvadchak, V.V.¬ (2019) α Synuclein dimers as potent inhibitors of fibrillization J Med Chem 62, 10342-10351.
Gaur, P., Kucherak, O.A., Ermakova, Y.G., Shvadchak, V.V., Yushchenko, D.A. (2019) Nitrobenzyl-based fluorescent photocages for spatial and temporal control of signalling lipids in cells, Chem Commun (Camb) 55, 12288-12291.
Afitska, K., Fucikova, A., Shvadchak, V. V., Yushchenko, D. A. (2019). α-Synuclein aggregation at low concentrations. Biochim Biophys Acta Proteins Proteom 1867, 701-709.
2018
Kyriukha, Y., Kucherak, O., Yushchenko, T., Shvadchak, V., Yushchenko, (2018) 3-Hydroxybenzo[g]chromones: Fluorophores with red-shifted absorbance and highly sensitive to polarity emission. Sensors & Actuators 265, 691-98
Shvadchak, V., Afitska, K., Yushchenko, D. (2018) Inhibition of α-synuclein amyloid fibril elongation by blocking fibril ends. Angew Chem 57, 5690-94.
Park, K., Kuo, Y., Shvadchak, V., Ingargiola, A., Dai, X., Hsiung, L., Kim, W., Zhou, H., Zou, P., Levine, A. J., Li, J., Weiss, S. (2018). Membrane insertion of- and membrane potential sensing by- semiconductor voltage nanosensors: Feasibility demonstration. Sci Adv 4, e1601453.
Shvadchak, V., Zgheib, S., Basta, B., Humbert, N., Langedijk, J., Morris, M. C., Ciaco, S., Maskri, O., Darlix, J. L., Mauffret, O., Fosse, P., Real, E. & Mely, Y. (2018). Rationally designed peptides as efficient inhibitors of nucleic acid chaperone activity of HIV-1 nucleocapsid protein. Biochemistry 57, 4562-4573.
Kucherak, O. A., Shvadchak, V. V., Kyriukha, Y. A. & Yushchenko, D. A. (2018). Synthesis of a Fluorescent Probe for Sensing Multiple Protein States. Eur J Org Chem, 5155-5162.
2017
Afitska, K., Fucikova, A., Shvadchak, V. V., Yushchenko, D. A. (2017). Modification of C-terminus provides new insights into the mechanism of α-synuclein aggregation. Biophy J 113, 2182-91.
Semerdzhiev, S. A., Shvadchak, V. V., Subramaniam, V., Claessens, M. (2017). Non-uniform self-assembly: On the anisotropic architecture of alpha-synuclein supra-fibrillar aggregates. Sci Rep 7, 7699.
Shvadchak, V. V., Kucherak, O., Afitska, K., Dziuba, D., Yushchenko, D. A. (2017). Environmentally sensitive probes for monitoring protein-membrane interactions at nanomolar concentrations. Biochim Biophys Acta 1859, 852-59.
2016
Zamotaiev, O. M., Shvadchak, V., Sych, T. P., Melnychuk, N. A., Yushchenko, D., Mely, Y., Pivovarenko, V. G. (2016). Environment-sensitive quinolone demonstrating long-lived fluorescence and unusually slow excited-state intramolecular proton transfer kinetics. Methods Appl Fluoresc, 4, 034004.
2015
Shvadchak, V. V., Claessens, M. M., Subramaniam, V. (2015). Fibril Breaking Accelerates alpha-Synuclein Fibrillization. J Phys Chem B, 119, 1912-18.
2014
Zamotaiev, O. M., Postupalenko, V. Y., Shvadchak, V. V., Pivovarenko, V. G., Klymchenko, A. S., Mely, Y. (2014) Monitoring penetratin interactions with lipid membranes and cell internalization using a new hydration-sensitive fluorescent probe. Org Biomol Chem, 12, 7036-44.
Shvadchak, V. V., Subramaniam, V. (2014) A four-amino acid linker between repeats in the alpha-synuclein sequence is important for fibril formation. Biochemistry 53, 279-81.
2013
Postupalenko, V. Y., Zamotaiev, O. M., Shvadchak, V. V., Strizhak, A. V., Pivovarenko, V. G., Klymchenko, A. S., Mely, Y. (2013) Dual-fluorescence L-amino acid reports insertion and orientation of melittin peptide in cell membranes. Bioconjug Chem, 24, 1998-2007.
2012
Strizhak, A. V., Postupalenko, V. Y., Shvadchak, V.V., Morellet, N. , Guittet, E. , Pivovarenko, V.G., Klymchenko , A.S., Mély, Y. (2012) Two-color fluorescent l-amino acid mimic of tryptophan for probing peptide–nucleic acid complexes. Bioconjug Chem. 23, 2434–43.
Giordano, L., Shvadchak, V. V., Fauerbach, J. A., Jares-Erijman, E. A., Jovin, T. M. (2012) Highly Solvatochromic 7-Aryl-3-hydroxychromones. J Phys Chem Lett 3, 1011-16 (52 cit.)
Pivovarenko, V. G., Zamotaiev, O. M., Shvadchak, V. V., Postupalenko, V. Y., Klymchenko, A. S. & Mely, Y. (2012). Quantification of local hydration at the surface of biomolecules using dual-fluorescence labels. J Phys Chem A 116, 3103-09.
2011
Shvadchak, V.V., Yushchenko, D.A., Pievo, R. and Jovin, T.M. (2011) The mode of alpha-synuclein binding to membranes depends on lipid composition and lipid to protein ratio. FEBS Lett. 585, 3513-9.
Shvadchak, V.V., Falomir-Lockhart, L.J., Yushchenko, D.A. and Jovin, T.M. (2011) Specificity and kinetics of alpha-synuclein binding to model membranes determined with fluorescent excited state intramolecular proton transfer (ESIPT) probe. J Biol Chem, 286, 13023-32.
Postupalenko, V. Y., Shvadchak, V. V., Duportail, G., Pivovarenko, V. G., Klymchenko, A. S., Mely, Y. (2011). Monitoring membrane binding and insertion of peptides by two-color fluorescent label. Biochim Biophys Acta 1808, 424-32.
Zamotaiev, O. M., Postupalenko, V. Y., Shvadchak, V. V., Pivovarenko, V. G., Klymchenko, A. S., Mely, Y. (2011). Improved Hydration-Sensitive Dual-Fluorescence Labels For Monitoring Peptide-Nucleic Acid Interactions. Bioconjug Chem. , 22, 101-07.
Greiner, V. J., Shvadchak, V., Fritz, J., Arntz, Y., Didier, P., Frisch, B., Boudier, C., Mely, Y., and de Rocquigny, H. (2011) Characterization of the mechanisms of HIV-1 Vpr(52-96) internalization in cells. Biochimie 93, 1647-58.
2010
Choulier, L., Shvadchak, V., Naidoo, A., Klymchenko, A., Mely, Y., Altschuh, D. (2010) A peptide-based fluorescent ratiometric sensor for quantitative detection of proteins. Anal. Biochem., 401, 188-95.
2009
Shvadchak, V.V., Klymchenko, A.S., de Rocquigny, H. and Mely, Y. (2009) Sensing peptide–oligonucleotide interactions by a two-color fluorescence label: application to the HIV-1 nucleocapsid protein. Nucleic Acids Res, e37, (3), e25.
Shvadchak, V.; Sanglier, S.; Rocle, S.; Villa, P.; Haiech, J.; Hibert, M.; Van Dorsselaer, A.; Mely, Y.; de Rocquigny, H. (2009) Identification by high throughput screening of small compounds inhibiting the nucleic acid destabilization activity of the HIV-1 nucleocapsid protein. Biochimie, 91, (7), 916-23.
Bilokin, M.D., Shvadchak, V.V., Yushchenko, D.A., Duportail, G., Mely, Y. and Pivovarenko, V.G. (2009) Dual-Fluorescence Probe of Environment Basicity (Hydrogen Bond Accepting Ability) Displaying no Sensitivity to Polarity. J Fluoresc., 19, (3), 545-53.
Bilokin, M.D., Shvadchak, V.V., Yushchenko, D.A., Klymchenko, A.S., Duportail, G., Mely, Y. and Pivovarenko, V.G. (2009) 3-Hydroxybenzo[g]quinolones: dyes with red-shifted absorption and highly resolved dual emission. Tetrah. Lett., 50, (30), 4714-9.
Spadafora, M., Postupalenko, V., Shvadchak, V.V., Klymchenko, Mely, Y., Burger, A., and Benhida, R. (2009) Efficient Synthesis of Ratiometric Fluorescent Nucleosides Featuring 3-Hydroxychromone Nucleobases Tetrahedron, 67, (37), 7809-16.
2008
Klymchenko, A.S., Shvadchak, V.V., Yushchenko, D.A., Jain, N. and Mely, Y. (2008) Excited-state intramolecular proton transfer distinguishes microenvironments in single- and double-stranded DNA. J Phys Chem B, 112, 12050-5.
de Rocquigny, H., Shvadchak, V., Avilov, S., Dong, C.Z., Dietrich, U., Darlix, J.L. and Mely, Y. (2008) Targeting the viral nucleocapsid protein in anti-HIV-1 therapy. Mini Rev Med Chem, 8, 24-35.
Avilov, S.V., Piemont, E., Shvadchak, V., de Rocquigny, H. and Mely, Y. (2008) Probing dynamics of HIV-1 nucleocapsid protein/target hexanucleotide complexes by 2-aminopurine. Nucleic Acids Res, 36, 885-96.
Pipko, S., Bezgubenko, L., Sinitsa, A., Rusanov, E., Kapustin, E., Povolotskii, M. and Shvadchak, V. (2008) Synthesis and structure of complexes of phosphorus pentachloride with 4-dimethylaminopyridine and N-methytimidazole. Heteroatom Chem, 19, 171-77.
2007
Yushchenko, D.A., Shvadchak, V.V., Klymchenko, A.S., Duportail, G., Pivovarenko, V.G. and Mely, Y. (2007) Modulation of excited-state intramolecular proton transfer by viscosity in protic media. J Phys Chem A, 111, 10435-38.
Yushchenko, D.A., Shvadchak, V.V., Klymchenko, A.S., Duportail, G., Pivovarenko, V.G. and Mely, Y. (2007) Steric control of the excited-state intramolecular proton transfer in 3-hydroxyquinolones: steady-state and time-resolved fluorescence study. J Phys Chem A, 111, 8986-92.
M’Baye, G., Klymchenko, A.S., Yushchenko, D.A., Shvadchak, V.V., Ozturk, T., Mely, Y. and Duportail, G. (2007) Fluorescent dyes undergoing intramolecular proton transfer with improved sensitivity to surface charge in lipid bilayers. Photochem Photobiol Sci, 6, 71-76.
2006
Yushchenko, D.A., Shvadchak, V.V., Bilokin, M.D., Klymchenko, A.S., Duportail, G., Mely, Y. and Pivovarenko, V.G. (2006) Modulation of dual fluorescence in a 3-hydroxyquinolone dye by perturbation of its intramolecular proton transfer with solvent polarity and basicity. Photochem Photobiol Sci, 5, 1038-44.
Yushchenko, D., Shvadchak, V., Klymchenko, A., Duportail, G., Mely, Y. and Pivovarenko, V. (2006) 2-Aryl-3-hydroxyquinolones, a new class of dyes with solvent dependent dual emission due to excited state intramolecular proton transfer. New J Chem, 30, 774-81.
Pipko, S., Simurova, N., Shvadchak, V., Bezgubenko, L. and Luk’yanenko, S. (2006) Dichlorophosphate anion in the synthesis of thioamides. Russ J Gen Chem+, 76, 1019-21.
Patent
Mely, Y., Langedijk, J., Shvadchak, V., Darlix, J-L. Peptides and antiviral drug, (2012) WO2012076822A1